Abstract:γ-Harmine, a new carboline alkaloid isolated from Peganum harmala L. (Zygophylaceae), has been shown to be 7-methoxy-4-methyl-γ-carboline (Ⅵ) according to its color reaction and spectral analyses. This is the first γ-carboline compound isolated from a plant, Harmine (Ⅰ) has also been isolated from the same plant material.