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ChineseJournalofBioprocessEngineering
Vol.11No.1
Jan.2013
doi:10.3969/j.issn.1672-3678.2013.01.015
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:1672-3678(2013)01-0087-07
Researchadvancesonthedevelopmentofmicrobicaloxygenaseand
itscharacteristicsincatalyzingbioreactions
NIEYao,FUMinjie,XUYan
(KeyLaboratoryofIndustrialBiotechnologyoftheMinistryofEducation,SchoolofBiotechnology,
JiangnanUniversity,Wuxi214122,China)
Abstract:Oxygenasewasakindofoxidoreductasesandcouldcatalyzeoxidationoforganiccompounds
withmolecularoxygen,thusitwaswidelyusedinindustriesofenvironmentdprotection,cosmetics,
pharmaceuticals,agrochemicals,andsoon.Oxygenasewassofardiscoveredandidentifiedfromvarious
microbialresources,suchasfungi,yeasts,bacteria,andactinomycetes.Inaddition,diferentmicrobial
oxygenaseswereexhibitedincatalyzingbiooxidationbothinreactiontypeandcharacterstics.Thispaper
summarizedtheresearchadvancesindevelopmentofoxygenasefromvariousmicrobialresourcesandthe
reactiondiversityperformedbydiferentoxygenasesinapplications.
Keywords:actinomycete;bacterium;diversity;fungus;oxygenase
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Table1 Oxygenasefromfungusandtheirpropertiesincatalyzingreaction
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=y((ôÔ V%× ¶ôT
/
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casicola,
Rhizopusoryzae
0T
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ÁY×
&VTòdç.«&1R
õö`
[21-22]
0TÔ
Alternariaalternata
0T
/─ òijÏÐôI%`&(A [23]
4 HBA
0TÔ
Phomopsis
liquidambari
0T
/4
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(4 HBA)
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[1]
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Pseudozymaflocculosa 0T/É4ÒÓ, V%dÒòeé&o}ñ [24]
N
0T((ô
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NMO Aspergilusfumigatus 0T/L?ø, òijAB@½%£¹ [2,25]
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,°
KMO
òÍ|BÅèsRHIqæ
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ñ
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Aspergilusnidulans ─ Ú¾Ü./0ôTÔoø(ôÔ
1R
[26]
Chocklet
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Fig.2 Hydroxylationofornithine
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aeruginosa,
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baumanni
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JK
:
[1] ChenY,PengY,DaiC,etal.Biodegradationof4hydroxybenzoic
acidbyPhomopsisliquidambari[J].ApplSoilEcol,2011,51:
102110.
[2] ChockletSW,SobradoP.AspergilusfumigantsSidAisahighly
specificornithinehydroxylasewithboundflavincofactor[J].
Biochemistry,2010,49(31):67776783.
[3]
£]
,
æQ
.
Y¦ñ(ôÔ
1
`235
[J].
MNmn
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2005,9(1):37.
[4]
^_
,
éA
,
âà`
.
Øø,TÔ`235
[J].
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