摘 要 ：采用L1210细胞株对美丽金丝桃(Hypericum bellum Li)的粗提物及其分步萃取物进行了细胞毒试验，结果表明，美丽金丝桃的氯仿及乙酸乙酯萃取物具有细胞毒活性，其IC50分别为54和60?μg/ml。在细胞毒试验结果指导下，同步对美丽金丝桃有效部位进行了化学成分分离。首次从该植物中得到3个化合物，通过理化数据测定及波谱数据分析，分别鉴定为4，4-二甲基-7α，8β-二羟基-3，5-二氧代二环［431］癸-1(10)-烯-2-酮(1)，槲皮素(quercetin，2)及木犀草素(luteolin，3)。其中，1为一新桥环化合物，并通过2D NMR分析，对黄酮类化合物2及3的 13C NMR谱中的C5和C9数据指认进行了修正。
Abstract:This paper applied ethnobotanical methodology to valuate the richness of medicinal plant resources in Ludian administrative village,Northwest Yunnan where has a long history of Naxi (Dongba) culture,based on community level.It analyzed the complex habitat,the diversity species and the richness traditional knowledge of medicinal plant resources in Ludian are fit with each other, and the comprehensive utilization factor has a close relationship with the rare and endangered factor.It discussed the communitybased sustainable management of medicinal plant resources should integrate with the local traditional culture and knowledge and practise into the actual use.It suggested to set up the specific conservation area for some special medicinal plant resources as the IN SITU conservation pattern in Ludian.