Abstract:A new steroidal compound, Dresigenin A, was isolated from the root of Dregea sinensis Hemsl. On the basis of mild saponification with 4% K2CO3/H2O+MeOH and spectral studies, its chemical structure was elucidated as 12- 0 -acetyl-20- 0 - ( 2 -methylbutyryl) dihydrosarcostin.