摘 要 ：本文报告龙胆科樟牙菜属植物青叶胆(Swertia mileensis T.N.Ho et W．L．Shih)中分到的两个微量内酯成分Ⅰ和Ⅱ。经UV.1H NMR.13C NMR．MS.证明Ⅰ是红白金花内酯erythrocentaurin),Ⅱ是一新化合物，命名为青叶胆内酯(swermirin)。探讨了青叶胆内酯和獐牙莱甙(eweroside)以及红白金花内酯之间的关系。认为青叶胆内酯是獐牙菜甙,獐牙莱苦甙(swertiamarin)的酶解分子重排游离甙元。此外还讨论了青叶胆内酯部分结构C7、C8、C10 碳核及与其相连氢核和甲基偏向高场的原因。
Abstract:The erythrocentaurin I and a new lactone II were isolated from Swertia mileensis T.N.Ho et W. L. Shin. in Yunnan (Chinese name: Qing Ye Dan). The yields of I and II were 0.003% (cald. from whole dry herbs). The II was named swermirin. The structure of swermirin was elucidated by means of UV. IR. 1H, 13C NMR and MS. It was assumed to be aglycone really which was obtained through intramolecular rearrangement by hydrolysis of sweroside and swertiamarin as Fig.2.