Abstract:A new hasubanan alkaloid,hernsubanine E(1),as well as two known compounds p-hydroxybenzaldehyde(2) and(-) syringaresinol(3) have been isolated from the whole plants of Stephania hernandifolia by various column chromatographic methods Their structures were identified by physicochemical properties and spectral analyses Compounds 2 and 3 were isolated from the genus of Stephania for the first time