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期 刊 ：中国中药杂志 2007年 32卷 17期 页码：1798.

关键词：慢性脑循环不足；心脑欣胶囊；疗效；

Keywords:chronic cerebral circulatory insufficiency, Xinnaoxin capsules, therapeutic effect,

摘 要 ：目的：观察心脑欣胶囊治疗慢性脑供血不足(CCCI)的疗效。方法：118例CCCI患者心脑欣胶囊治疗组60例,尼莫地平对照组58例,两组其他治疗方法一样,疗程4周。采用经颅多普勒彩超(TCD)观察两组治疗前后脑动脉平均血流速度(Vm)的变化,检测血液流变学指标的改变及观察不良反应。结果：治疗组总有效率88.3%,与对照组(70.7%)比较,有显著性差异(P<0.05),治疗组改善血液流变学、脑部血液动力学等指标方面均优于对照组(P<0.05)。结论：心脑欣胶囊治疗慢性脑循环不足疗效肯定。

Abstract:Objective: To observe the therapeutic effect of Xinnaoxin capsules in patients with chronic cerebral circulatory insufficiency. Method: Patients with chronic cerebral circulatory insufficiency were divided randomly into two groups: a Xinnaoxin capsules group (n=60, treated by Xinnaoxin capsules for four 4 weeks), a control group (n=58, treated by Nimodiping for four weeks). The transcranial doppler (TCD) was used to determined mean velocity (Vm) and auto-viscometer measured hemorheological indices before and after being treated. Result: After 4 weeks treatment, the hemorheological indices and mean velocity were obviously improve in Xinnaoxin capsules group (P<0.05), there is significant difference between the effective rate of two groups (88.3%, 70.7%). Conclusion: Our study suggest that Xinnaoxin capsules have therapeutic function on chronic cerebral circulatory insufficiency.

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