Abstract:A comparative study was made on the dissolved amount of poisonous trace elements mercury and arsenic con-ained in hydrargyri subchloridum and realgar of gynecological suppository in artificially simulated vaginal acid-base li-quid with that contained in hydrargyri subchloridum and realgar in artificial gastric juice stipulated in Phaimacopeia ofChina , The result shows that the dissolved amount of mercury and arsenic contained in the suppository is much smallerhan that stipulated in Pharmacopeia for oral administration.