Abstract:Embryonic skin fibroblast of Sprague-Dawley rats cultivated in vitro was used in this experiment.The culturalmedium was added with absorbable components of several drugs. The result reveals that Yan Shou recipe, vitamin Eand Huan Jing Jian have conspicuous promotive effect on the growth of diploid fibroblast and also help to increase pop-ulation doublings. The experiment suggests that all these drugs poxsess anti-aging effect on the skin diploid fibroblastof rats.