Abstract:This paper deals with the effects of Radix Aconity Kusnezoffii and Radix Aconity Kusnezoffii processed by a newmethod of moistening and steaming,and by pharmacopoeial routine on acute toxicity,cardiac rhythm and respiration.The result shows that the Radix Aconity Kusnezoffii processed by new method No 1.,which applies moistening in wa-ter for 48h and then heating w1th high pressure stearn(68. 65kPa,115℃)for 2h,has the advantages of lower toxicity,and lesser inhibitory effecton cardiac rhythm and respiration .