Abstract:Muskrat and musk are secretions from the fragrant glands of male adult musk-rats(Ond(?)trazibethica)and musk-deers(Moschus moschiferus)respectively,in this paper,the pharmacologicalactivities of the muskrat and musk are compared.The results show that both are antiflamma-tory,antihypnotic(pentobarbitalum natricum)and antibacterial and both can increase theresistance against hypoxia.This suggests that muskrat may be used as a substitute for musk.