Study on relationship of properties and drug release rate of hot melt pressure sensitive adhesive Optimization of Guanjie Zhitonggao Patch formulation using central composite design-response surface methodology Study on matrix proportion of hydrophilic SIS hot melt pressure sensitive adhesive suit modified by RLPO Optimization of Guanjie Zhitonggao Patch formulation using central composite design-response surface methodology Advances in studies on hot melt pressure sensitive adhesive applied in patches of Chinese materia medics