免费文献传递   相关文献

Effect of prescriptions replenishing vital essence, tonifying Qi and activating blood on TNF-α, IL-1β expressions in serum and submaxillary gland of NOD mice with Sjogren‘s syndrome

养阴益气活血方药对干燥综合征NOD小鼠血清及颌下腺TNF-α,IL-1β表达的影响



全 文 :|K}~B‹,Ðy€$‚
;JK
:EBi’
ƒ„…
C;L4
!
$ :B4
IJƒ×Ø
s¬ú

!
Wûü
*
!
!
ý>œ
)
!
þ¬ÿ

d
ëÎÆr qrs íî¸üqs
!
ëÎ ì«
)$$$)&
*d
ëÎ}qvÆr
!
ëÎ ì«
)$$))& )d
&w°}qqs
!
:~ &w
#$$$#

jk
#!

#
o.|K}~B‹,Ðy€$‚
!80.QWF1iTT51XW./F$88$1.14.^FTFXHR^FUH-!;JK
:EBi’ƒ„
…‚†ö÷okÉÁ
4
!
!UY/.W1F-W.THTVR-U.W4
!
$C;L4
!
%
*øù.;
4G

!H1UFWGFY\H14G

$:B4


IJƒ×Ø
+
„…
# )*
ú
;JK
:E`ø»ßßà‚
%
$,‚
%
Úí>‚
%
$P,‚
$

(
ú
ZRG^=<
:E|ß`4ÐÆ
!
`4‚
+
$,‚w°¸
$$ Q-
\Q
f
¯|K}~Bùª
$d& /B$
Úí>‚w°¸Æ
#$ /Q-\Q
f
ªº¯Úí>
$d& /B,
$P,‚w°¯$,|K}
~Bùª
!$ Q-\Q
f
c
Úí>
!#$ /Q-\Q
f
$d& /B+
RS†f
(
+– ›o”B
$
;k:E
$
J?ƒ”ƒ„…‚†
$
®
C;L4
!
$:B4
À?
$
ef‚†DŒä ƒ„…‚†
C;L4
!
$ :B4
H*ƒIJ
+
†‡
#
ßà‚
;JK
:EB
iGƒ„…‚†
C;L4
!
$:B4
À?êëA~õëp‚
!0t$d$+
`4‚Bi
C;L4
!À?¹~õëp‚
$
ϙ$,‚ã
‚Ï…s
,
$,‚
%
$P,‚Bi
:B4
À?¹~Úí>‚
!0t$d$$
™`4‚ãêëÁ¹
+
$,‚
%
$P,‚
C;L4
!H
*IJ™`4‚ãêëÁ¹
$
g$P,‚êë¹~Úí>‚
!0t$d$+
$P,‚
:B4
IJ™`4‚ãêëÁ¹
+
†ˆ
#
|
K}~Bùªä„Py€$‚
;JK
:EBiGƒ„…
C;L4
!
$:B4
À?
$
|K}~BùªõäB—PQ
CS=CS*
ø
ùÉÁÀ?
$
Åæ烄…î¸k¤
$
JØMN
88
ƒ|}
+

lmn
#!
y€$‚
,;JK
:E
,
|K}~B$,
,C;L4
!
,:B4


op-F
#!*$*$($$$(

qrsP
#!
cªº$Ã,øgÚ
!*$$_Z$

thuv
#!
!
™°ï
$
@´¼
$M4/RHG#GHUHR15H$$$$$25RS..,-./,-1
!!
y€$‚
!80.QWF1iTT51XW./F$88
Ñï³¥
@Aõ…
%
B…÷—»f…ƒ›£‚£(ÿef
£#î
$
õîÉGeîø•ù/i»
+
䚓’
›²RScR
$88
³^’
88
›²ßà—»f…g
1’oÿƒ
:B4
G
C;L4
!IJêëbP
$

:B4
êëKu•…“»fãä
./
+
ÂâRSc
Ž
$C;L
¦¦ªMN
88

.*/
$
a!/Âïþ;Ð
êý
C;L4

88
D—˜$rBƒþÓ|
}
+
ZRSB—„…$,|K}~BùªÐy€
$‚
;JK
:EBi’ƒ„…‚†
CS
àøùÉ
Á
C;L4
!G
CS*
àøùÉÁ
:B4
ƒ×Ø
$
/øù
ÉÁþ;¤¥õMN
88
ƒ|}ø•
+
!
Ȟ
]!
›²
é›
;JK
:E
&(
ú’
ZRG^=<
:E
(
ú
$(
+
2
$

$

8AL
Ô
$
~ã6_îÃcÆM;G
r;yz„¢|
+
RS›²îbM±C؛²R
S$X“Ä
+
›²$»c<
*$$%$$$**#+
](!
,n
$,|K}~Bùª
!
î¦Á›
*& Q%
*z
Q%
Wp
* Q%
¸Á
$ Q%
Šq
Q%
ãT
$ Q%
%
°
Q%
öQq
* Q%
*D
Q%
$%
* Q
÷$,
‚ò
#
rG$,îïÖ~cªDÃQä°
vïÃQ$,P
$
îcª$Ã,D$,RS…ù
•N’ò6Â,ºß
# Q-/B
f
+
ëLÚí>ïî
bM$P•,GHIJÂ#
$

$d Q=
ï
$
i<
$7$$(+
}øpÀß!ò6,º
) Q-B
f
+
]&!

:E
C;L4
!
$:B4
®!MB:83
Œ

*ª«ä Ö(bMíE²&(GHIJ
,
ƦE
C;L4
!
$:B4
äØü¦“ï¦
!
a2¬M²t˜b
eGHIJ»÷×%
83;C3<>@_
IJ#n
,

8E47$$$Ah47$$)
Ö(23$è«7IJ
+
(!
‹Œ
(]!
»‚
ã
)*
ú
;JK
:E`ø»ß
&
‚
$
zßà‚
%
$
-)&-
v
)(
²v
)
x
*$)
q
*
r
!!!!!! ! ! ! ! ! !!!! ! ! ! !
].Gd)($ :TTYF!)
LF^WYRW5$ *$)

%
Úí>‚
%
$P,‚
$

(
ú
+ ZRG^=<
:E
(
úÈß`4ÐƂ
!
`4‚
+
RS›²¢|~
ã6_îÃcÆM;Gr;yz„
$
îÀ/•À
+
(](!
•,‹Œ
`4‚Gßà‚w°`4Ÿ|
+
p•,‚ž`
4Ÿ|Ûáb
$
~RSb\–w°ÆT•,

.
$
•
,º¸›²™š÷ ªºQøIÏø
+
$,‚w°
¸Æ
$$ Q-\Q
f
ªº»Ì¯|K}~Bùª
$d& /B+
Úí>‚w°¸Æ
#$ /Q-\Q
f
ªº¯
Úí>ïß!õ
$d& /B,
$P,‚w°»Ì¯$
,|K}~Bùª
c
Úí>
!
|K}~Bùª
$ Q-\Q
f
c
Úí>
#$ /Q-\Q
f
$d& /B+
RS†
f
(
+– ›oHB
$
;k:E
$
J?ƒ”ª„ƒ„
…†fåæä 
+
(]&!
o.åæ
(]&]!
Bi
C;L4
!G
:B4
À?ä 
!
RSŠß
–
$
ãH”ƒ:EBiGBi»ÄÃ$
$
…M¾
)$ /H1$
Ù
) $$$ W-/H1
f
ÄX
/H1
ȀBi
$
Ž
”BiG
d /B
ÄXÃ$
$ & k
qt
$
)}
MB:83
Œ ÆBi
C;L4
!
$:B4
À?
+
²»¸Æ*
ª«Ðêjd#î|
+
(]&](!
ƒ„…‚†
C;L4
!G
:B4
H*6ºä 
!
)}ef‚D
8A
Œä :Eƒ„…‚†
C;L4
!
G
:B4
H*6º
+
͓d#²»¸ÆÐêj
î|
+
i7»¼’Š3»¼
#
)}äãä\…êøù
id»¼Ã¸‚†fi7»¼
$
é”
&$$
éi7
$
øù´øù>s›ŠêßÉ£IJøù
+
é›G…
sƒ‚†¢
$
€×å
%
/<
%
)j
%
»¼
%
F”?â
+
`øé”

T8džf?ܝ; Æ
$
”õ?
Œ|ßZDïƒUIŒ†f‚Ï»¼
+
(]^!
‚Ï»¼
RS?â}
8A88 d$
™z‚Ï»¼
+
켵
ž)}
7u$$
‚tœ)}
J1F4NR53;J]3
äS
‹Œ
+
»¼Š3Ù
0t$d$
ßÁ¹G‚Ï…s
+
&!
Š3
RS®v
*
+
$
$,‚G

ú:Eke
$
€J?
–e‘Ñɯ/sABMÃklgk
+
&]!
:EBiøùÉÁ
C;L4
!
$:B4
6ºƒœ
ßà‚
;JK
:EBi
C;L4
!
$:B4
6º
A~õëp‚
$
‚ÏÍGëä£Á¹
!0t
$d$ +
`4‚Bi
C;L4
!À?¹~Úí>
‚
%
$P,‚
!0t$d$ $
g™$,‚ã‚Ï
…s
,
$,‚
%
$P,‚Bi
:B4
À?¹~Úí

$
‚ÏÍGëä£Á¹
!0t$d$ $
™`4
‚ãêëÁ¹
$
UI
+
I
!
p‚:EBi
C;L4
!
$:B4
6ºœ
!

7u$
CR^GF!<./ERWHT.1 .VC;L4
!
R1X :B4

H1 TFWY/.VFR-S
QW.YE /H-F!

7u$ 1Q-B
f
‚Ì
* C;L4
!
:B4

`4
( *(%d#7
u)d&(
*
$$d)
u$d)
*
ßà
( &*#d#$
u7d)

**d*)
u*d)

$,
% )*(d
u&d&
*
(d#(
u(d(7
*$)
Úí>
( )#d7
u*d*(
$*
&(d*%
u#d%
$ *
$P,
( )*7d#
u&d&
$*
*d
u$d&#
*$ )
!!
¨
#
™`4‚œ

0t$d$,
™ßà‚¢œ
*
0t$d$,
™Úí
>‚¢œ
)
0t$d$!
I
*
0
+
&](!
:Eƒ„…‚†
C;L4
!
$:B4
ƒIJ
&](]!
ef‚D
8A
Œä Š3
!
ef‚†D
8A
Œ„…e‘
$
ßà‚
;JK
:E„ƒ…‚†D
1»…gƒï>
%
ۄ>
%

%
\Ãbp8G
Ò¦êƒ
C;L4
!›Šê¦ê€Í
,
`4‚:E
ƒ„…ƒ…g
%

%
\Ã÷;¦ê<ø†¢
,
Úí>‚1»GÃ
%
\҅ù8›Šê€Í
¾
$
Ϝ$,‚G$P,‚¦ê˜;Ò
+
`4‚
:Eƒ„…‚†íU›Šê€Í
:B4
IJ
$
ß
à‚
;JK
:Eƒ„……gƒÛí>
%
\ÃÛí
>÷;õU
:B4
ÒIJ
$
g$,‚
%
$P,‚
GÚí>‚:Eƒ„……gƒÛí>
%
\Ã÷;
G՞IJ
$
è$P,‚
%
$,‚IJ<
$
U
i
$*+
&](](!
:Eƒ„…‚†
C;L4
!
$:B4
?ŽÜ;
œ
!
ßà‚:Eƒ„…
C;L4
!
$:B4
?ŽÜ;
A~õëp‚
$
‚ÏÍGëä£Á¹
!0t$d$+
`4‚ƒ„…
C;L4
!
$:B4
H*IJ¹~õëp
‚
,
Ï$,‚
%
$P,‚
C;L4
!H*IJ™`4‚
ãêëÁ¹
$
g$P,‚êë¹~Úí>‚
!0t
$d$,
$P,‚
:B4
IJ™`4‚ãêëÁ¹
$
UI
*+
^!
¥0
ÚÛ
$ 88
ƒSDƒîÉGeîø•ù/ê
S
.)/
+
ï—ÜßÑT“žOElSÛáb
$
îRB
É;ôe
+
ˆä„…Iê
88
ƒH…
%
B…$GDº
-&&-
v
)(
²v
)
x
*$)
q
*
r
!!!!!! ! ! ! ! ! !!!! ! ! ! !
].Gd)($ :TTYF!)
LF^WYRW5$ *$)
!!
3d
`4ÐƂ
,Zd
ßà‚
,$,‚
,Kd
Úí>‚
,Md
$P,‚
!
i
*
0
+
i
!
:Eƒ„…‚†
C;L4
+ƒIJ
!
ef‚D
$K3Z
¦
ê
$o&$$
LHQd!M6EWFTTH.1 .VC;L4
+
H1 TY^/R1XH^YGRWQGR1XT.VFR-S
QW.YE /H-F!H//Y1.SHTU.-SF/HTUW5$ K3ZTURH1H1Q$o&$$
i
*!
:Eƒ„…‚†
:B4
ƒIJ
!
ef‚D
$K3Z
¦
ê
$o&$$
LHQd*!M6EWFTTH.1 .V:B4

H1 TY^/R1XH^YGRWQGR1XT.VFR-S
QW.YE /H-F!H//Y1.SHTU.4-SF/HTUW5$ K3ZTURH1H1Q$o&$$
ƒ
C
øù*T
.&/
$
gèah*Tƒ
C
øùõ\i…
Ãbpš•*øù¦§
!?B34K>
ƒ—;IJ
$
G
»fDºƒ{#£øùÉÁ
$

:B4
G
C;L4

$
!!
I
*!
:Eƒ„…‚†
C;L4
!
$:B4
?ܝ;œ
!

7u$
CR^GF*!<./ERWHT.1 .V/FR1 .EUH-RGXF1THUHFT.VC;L4
!
R1X :B4


H1 TY^/R1XH^YGRWQGR1XT.VFR-S QW.YE /H-F!

7u$
‚Ì
* C;L4
!
:B4

`4
(
$d u$d$&
*
$d$( u$d$
*
ßà
(
$d) u$d$(

$d# u$d$

$,
%
$d& u$d$
*
$d* u$d$%
$*
Úí>
(
$d) u$d&
$ *
$d*% u$d$
$ *
$P,
(
$d7 u$d$#
*$)
$d( u$d$7
*
Ì`éo»f£\Ã
$
/g©…“éo
+
G„…ë
û
CSG
àøùÉÁgAž
88
eî$BþÓ|}
$
L.6
÷
./
„…e‘
88
³^I…‚†$ƒ
:B4$:B4#$
C;L4
!ƒÀ?êëA~`4ÐÆ^
+

CS
¢¡
ƒøùÉÁ
!:B4*$:L;4

$:B4*$:B4($C;L4
!

Ñ
88
³^Aõ…tžƒÒÓøùÉÁ
.#/
+
$,|K}~BùªÒÓî¦Á›
%
*z
%
W
p
%
¸Á
%
Šq
%
ãT
%
%°
%
öQq
%
*D
%
$%
÷$,‚ò
$
ÍG´@|K
%
}~Â_
%
BDö3
ã
$
G ºÐK¶~¶JBöîø
$
JØMN
88
3
ڃ
+
ž}ªRS„…$e‘
$
$,|K}~B
ùªäìæç
;JK
:EwsîÀºGAõ»fº
$
æç:Eƒ„…ƒK Š*Tî¸k¤
.%/
+
ZR
SŠ3ëûßà‚
;JK
:EBiGƒ„…‚†
C;L4
!
$:B4
À?êëA~`4‚
$

88

AÀ?ƒ
CS$CS*
àøùÉÁ
+
€}|K}~
B$,MN–
$
$,‚
%
$P,‚Bi
:B4
À?¹
~Úí>‚
+
$,‚
%
$P,‚
C;L4
!H*IJ™
`4‚ãêëÁ¹
$
g$P,‚êë¹~Úí>‚
+
$P,‚ƒ„…
:B4
IJ™`4‚ãêëÁ¹
+
“û$,|K}~BùªäL¹
88
Bi’ƒ„
…øùÉÁƒÀ?
$
PQ
CS=CS*
ef?­
$
/g
JØMN
88
ƒÚƒ
$
õ͓MNø•ã†ïdFG
„…
+

wxyz
#
./!_.Y\SWHK$?.XQFT>>$Z5.1 K$FURG,>.GF.VEW.H1VGR//RU.W5-54
U.\H1FTH1 USFH/ERHWFX GR-WH/RUH.1 RTT.-HRUFX +HUS RYU.H/4/Y1F
6FW.ESUSRG/HR.I/,:1hFTUJESUSRG/.G]HT8-H$*$$*$&)#&*7,
.*/!C./+RGX I$L.6?$MX+RWXT<$FURG,CWFRU/F1U+HUS EFQ5GRUFX WF4
-./^H1R1U/FUSH.15GSY/R1 T.GY^GFUY/.W1F-W.THTVR-U.W4U5EF WF4
-FEU.W!AMOTC;L4> EWFhF1UTXFhFG.E/F1U.V80.QWF1iTT514
XW./FR1X XHR^FUFTH1 USF;JK /.YTF/.XF .I/,3WUSWHUHT
>SFY/$*$$$$&*!8YEEG7#&$)d
.)/!>YXX58$?RWHTMK$ IW8GFX5FU.G.Q5.9/,ASHGRXFGESHR#NZ8RY1XFWT<./ER15$*$$#$*(d
-&-
v
)(
²v
)
x
*$)
q
*
r
!!!!!! ! ! ! ! ! !!!! ! ! ! !
].Gd)($ :TTYF!)
LF^WYRW5$ *$)
.&/!NHGF\FA$ 8-S.UF?$ 8-SGYUFWZ$FURG,:1UFWGFY\H1 ^FURR1X
UY/.YW1F-W.THTVR-U.WRGESRTF-WFUH1Q-FGTRWFH1-WFRTFX H1 USFEF4
WHESFWRG^G..X .VERUHF1UT+HUS EWH/RW580.QWF1iTT51XW./F.I/,
311 >SFY/KHT$*$$)$#*#)7d
./!L.6>:$bR1Q?:$31X.K$FURGd<5U.\H1F/>;3F6EWFTTH.1 H1
TRGHhRW5QGR1X ^H.ETHFT.V80.QWF1iTT51XW./F.I/,I://Y1.G$
77&$*!#)*,
.#/!MXQRWX.<$b.G\.+T\$AFUFW>$FURGdCS EWFX./H1R1-6R1X EFWV.WH1
F6EWFTTH.1 H1 /H1.WTRGHhRW5QGR1XTV.W/ ERUHF1UT+HUS EWH/RW5
80.QWF1iTT51XW./F.I/,I3YU.H//Y1HU5$777$)#d
.%/!
U%<
$
ßEY
$
™°ï
$
÷
d
|K}~BŒÐy€$‚
;JK
:Eƒ„…ƒyÐ|}„…
.I/,
P1$Ã,
$*$*$*
!##*7d
*K?RB@KLE?IRE.LB.@AIE?L/?A.IC.AS P.B-/?II?AR?$ B@A.KD.AS Y.-AF-RB.P-B.AS
J/@@F@A=3:+
!
$ 29+

?NLE?II.@AI.AI?EG,-AFIGJ,-N./-ED
S/-AF@K36>,.R?T.BC;U@SE?A[IIDAFE@,?
N@OY.4GH1

$ B:CHR145H
*
!
$ A@ H`1Q4S.1Q
)
$ P@OY.45.Y

!d@,&$+8/,2,%+#5 H.$?,+%2$ =.2#3#./9#5,,*#$ T(#<,%*3 K*,F#&$,+4$ H%*3E(.- )$$$)$ =(,*%,
*dT(#<,%*3 =(,*#$#9#5,%2K*,F#&$,+4$ H%*3E(.- )$$$)$ =(,*%,
)dX-<,*3 6&%5,+,.*%2=(,*#$#9#5,%2H.$?,+%2$ X-<,*3 #$$$$ =(,*%
.4JIBE-RB/!6JU?RB.P?# C..^TFWhFFVF-U.VEWFT-WHEUH.1TWFEGF1HTSH1QhHURGFTTF1-F$ U.1HV5H1QDHR1X R-UHhRUH1Q^G..X .1 F64
EWFTTH.1 .VUY/.W1F-W.THTVR-U.W4
!
!C;L4
!
R1X H1UFWGFY\H14G

! :B4

H1 TFWY/R1X TY^/R6HGRW5QGR1X .V1.14.^FTFXHR^FUH-
!;JK /H-F+HUS 80.QWF1iTT51XW./FdUWRXHUH.1RGH1 FR-S QW.YEdMHQSUZRG^=XF-.-UH.1 WFEGF1HTSH1QhHURGFTTF1-F$ U.1HV5H1QDHR1X R-UHhRUH1Q^ G..X !$$ Q-\Q
f
FhFW5XR5, USFS5XW.65-SG.W.aYH1FQW.YE +FWF
QHhF1 $d& /BS5XW.65-SG.W.aYH1F!#$ /Q-\Q
f
FhFW5XR5, USFC<9N9QW.YE +FWFQHhF1 $d& /BXF-.-UH.1$ WFEGF1HTSH1QhHURGFT4
TF1-FU.1HV5H1QDHR1X R-UHhRUH1Q^ G..X !$ Q-\Q
f
R1X S5XW.65-SG.W.aYH1F!#$ /Q-\Q
f
FhFW5XR5d9H-F+FWFTR-WHVH-FX RVUFW
FHQSU+FF\T$ R1X USFHWRWUFWHRG^G..X R1X UHTTYFT.VTY^/R6HGRW5QGR1X +FWF-.GF-UFXdCSFGFhFGT.VC;L4
!
$:B4

H1 TFWY/+FWFXFUF-4
UFX ^5MB:83dM6EWFTTH.1T.VC;L4
!
$:B4

EW.UFH1 H1 TY^/R6HGRW5QGR1X +FWFXFUF-UFX ^5H//Y1.SHTU.4-SF/HTUW5d8?IG/B#<./ERWFX
+HUS .USFWQW.YET$ C;L4
!
$ :B4

H1 TFWY/R1X TY^/R6HGRW5QGR1X H1 USF/.XFGQW.YE +FWFSHQSFW!0t$d$dCSF1.W/RGQW.YE
TS.+FX G.+FWTFWY/C;L4
!
GFhFGUSR1 .USFWQW.YET!0t$d$$ ^YU+HUS.YUTURUHTUH-RGTHQ1HVH-R1-F-./ERWFX +HUS USFC<9QW.YEd:B4


H1 TFWY/H1 USFC<9QW.YE R1X USFC<9N9QW.YE +FWFG.+FWUSR1 USRU.VUSFS5XW.65-SG.W.aYH1FQW.YE !0t$d$$ ^YU+HUS.YU
TURUHTUH-RGTHQ1HVH-R1-F-./ERWFX +HUS USF1.W/RGQW.YEdC;L4
!
EW.UFH1 F6EWFTTH.1 H1 USFC<9QW.YE R1X USFC<9N9QW.YE TS.+FX 1.
THQ1HVH-R1UXHVFWF1-F-./ERWFX +HUS USF1.W/RGQW.YE$ +SFWFRTUSFC<9N9QW.YE +FWF1.UR^G5G.+FWUSR1 USRU.VUSFS5XW.65-SG.W.4
aYH1FQW.YE !0t$d$d:B4

F6EWFTTH.1 H1 USFC<9N9QW.YE TS.+FX 1.THQ1HVH-R1UXHVFWF1-F-./ERWFX +HUS USF1.W/RGQW.YEd
0@AR/GI.@A# CSFXF-.-UH.1 WFEGF1HTSH1QhHURGFTTF1-F$U.1HV5H1QDHR1X R-UHhRUH1Q^G..X -R1 XF-WFRTFUSFGFhFGT.VC;L4
!
$:B4

H1 TF4
WY/R1X TY^/R6HGRW5QGR1X .V;JK/H-F+HUS 80.QWF1iTT51XW./Fd:U/R5H/EW.hFERUS.G.QH-RGXR/RQF.VTY^/R6HGRW5QGR1X ^5WFQY4
GRUH1QCS=CS* -FGVR-U.WT$ H1 .WXFWU.R-SHFhFUSFUSFWREFYUH-FVF-U.1 88d
._?D T@EFI/!80.QWF1iTT51XW./F, 1.14.^FTFXHR^FUH-/.YTF, UWRXHUH.1RGV5H1QDHR1X R-UHhRUH1Q^ G..X, C;L4
!
, :B4

F@.#)X^(`ORUR,,()&)&(^

{|-0
!
›œ
#
-#&-
v
)(
²v
)
x
*$)
q
*
r
!!!!!! ! ! ! ! ! !!!! ! ! ! !
].Gd)($ :TTYF!)
LF^WYRW5$ *$)