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期 刊 ：中国中药杂志 2008年 33卷 20期 页码：2404.

关键词：药穴结合；溃疡性结肠炎患者；临床疗效；血清超氧化物歧化酶；一氧化氮；

Keywords:combination between medicine and acupoint, patients with ulcerative colitis, clinical curative effect, SOD, NO,

摘 要 ：目的：探讨药穴结合对溃疡性结肠炎(UC)患者临床疗效及血清超氧化物歧化酶(SOD)、一氧化氮(NO)的影响。方法：将UC患者262例随机分为四组：中药组口服肠癖康；耳穴组耳穴贴压脾、大肠、交感、皮质下；药穴组口服肠癖康加耳穴贴压；对照组口服柳氮磺胺吡啶。4周为1疗程。治疗前后观察各组NO,SOD。结果：4组治疗前后差异有显著性(P＜0.05)，药穴组与其他3组比较，差异有显著性(P＜0.05)。结论：药穴结合可增加SOD的含量，降低NO的含量，提高机体清除体内氧自由基，促进肠道溃疡愈合。

Abstract:Objective: To investigate the clinical curative effect of the combination between medicine and acupoint flow on SOD, NO in patients with ulcerative colitis. Method: Two hundred sixty two patients with ulcerative colitis were randomly divided into four groups: the patients in traditional Chinese medicine group were fed with changpikang, the patients in ear acupoint group were pasted and pressed spleen, large intestine, sympathesis, subcortex; the patients in medicine and acupoint group were taken with Changpikang and ear acupoint; the patients in treatment group were treated by taking sulfasalazine,with a treatment course of four weeks. The changes of SOD, NO before and after treatments were recored. Result: There was a significant difference between four groups before and after treatment (P<0.05), medicine and acupoint group was superior to that others (P<0.05). Conclusion: The method of combination between medicine and acupoint could Increase the contents of SOD, decrease the level of NO, elevate the potential of organism to resist oxygen free radical and promote intestinal tract ulcer concrescence.

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