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期 刊 ：中国中药杂志 2005年 30卷 14期 页码：1099.

关键词：敏咳清口服液；过敏性咳嗽；IL-6；IL-8；ET-1；TXB2；

Keywords:Minkeqing oral liquid, allergic cough, IL-6, IL-8, ET-1, TX-B,

摘 要 ：目的:观察敏咳清口服液治疗小儿过敏性咳嗽的疗效、探讨其细胞分子生物学作用机理。方法:将大鼠用卵蛋白吸入法造模、观测敏咳清口服液对模型动物血液、支气管-肺灌洗液中IL-6,IL-8,ET-1,TXB₂的影响。结果:敏咳清口服液能降低模型动物血液、支气管-肺灌洗液中IL-6,IL-8,ET-1,TXB₂的水平。结论:敏咳清口服液具有明显的抑制炎性介质释放的作用。

Abstract:Objective: To observe the effect on infantile allergic cough with Minkeqing oral liquid (Minkeqing) and to study its cell molecular biologic mechanism. Method: The rat model was induced by inhalating ovalbumin; then the effects of Minkeqing on IL-6, IL-8, ET-1, TX-B₂ in the blood and the bronchoalveolar lavage fluid (BALF) of the animal model were obsered. Result: Minkeqing could reduce the levels of IL-6,IL-8,ET-1 .Tx-B₂ in the blood and BALF of the animal model. Conclusion: Minkeqing has the significant function of inhibiting the release of inflammatory mediums.

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