Abstract:Objective:To study the effect of the total oil of Microula sikkimensis on an experimental hyperlipemia model of rat.Method:Using feeding method to set up the experimental hyperlipemia model and determining the biochemical criteria .Result:The total oil of Microula sikkimensis significantly decreased the contents of cholesterol,triglyceride and MDA in blood serum,and increased the rate between total cholesterol and high density lipoprotein.Conclusion:The study provides an important basis for exploiting and utilizing the total oil of Microula sikkimensis.