Abstract:Four compounds were obtained from the leaves of Hydrangea macrophylla and identified by chemical and spec-troscopic methods as hydrangenol (Ⅰ),hydrangenol-8-O-glucoside(Ⅱ) , hydrangenol-8-O-galactoside(Ⅲ)and hy-drangenol-4′-O-glucoside(Ⅳ).Ⅲ and Ⅳ are two new natural products。