Abstract:Climate change with global warming as the sign has been caught great attention by the governments, international organizations, and scientists in the world. Human society and natural e- cosystem are both exposed to climate change, and more and more people are waked up by its in- creasing harm. Vulnerability analysis and assessment are the key and basis for adapting and mitiga- ting climate change, being the highlight in the research fields of climate change and ecology in re- cent years. The vulnerability assessment of climate change is being carried out in various research fields and on different scales, and much progress has been made. This paper introduced the concept of vulnerability, and summarized the research progress in vulnerability assessment of climate change, with the focus on the frame and methodology of vulnerability assessment of natural ecos- ystem response to climate change. The existed problems and future prospects in this research area were also discussed.