免费文献传递   相关文献

Incidence rate of adverse reaction/event by Qingkailing injection: a Meta-analysis of single rate

清开灵注射液不良反应/事件发生率的Meta分析



全 文 :)$5
x
)
y â
&$
ãâ
)&
|
U-@c&$$ ;-+)& JH,H.BHR$ )$5
žÝÞ³´µ‘’
=
ßàláâ–
9HMA
ƒ˜
4LM
!)
!
#$%

!
CNO
)
!
&23

!
!

!
c
,-,67É8 ,69:;<6É=>?
!
@A
$$%$$% )+
~L,6XÍÉ €68
!
s ~L
4$$)#

wx
#!
^[õWÉ~%žÝÞ³´µ‘’
=
ßàláâ
+
¯d¸›‡
NTB9HI$K9BACH$MQH<-,QRA0H@?BRAR6$<;b:$U:N$
DA0aA0XJAMA
 
wž=‚«›‡O(oò‹«O(s
)$5
x
%
y
4$
z
+
È
)
·ˆ‰ôO‚Âeœ(9vc^Ä
*
Ž¯°é«Îõ¬
$

>4c)c$
xà5m
9HMA
ƒ˜
$
é:`Cƒ˜
+
)±{F
#
:=ÂA
#4
å^Ä
$( %(4
«žÝÞ³´
µ—,ô
,
ê¯lá
4#%
«‘’
=
ßà
$
ì$©Oë,*‘’
=
ßàláâ
)i-(5i<:!$c$),$c$4.,
K_õW
‘’
=
ßàláâò
#i-(5i<:!$c$5,$c$%.,
³´1·‘’
=
ßàláâò
&i-(5i<:!$c$),$c$%.+
ícK_õW
òÄ`Pܖ‘’
=
ßà…»$
$
’, ›²láâƒRò
&c#i-$c$) ,$c$(% %.$#c(i-$c$54 5,$c$( .,
íc©O
ë,*2ˆòÄ`P܏‘’
=
ßà…»$
$
ÎÏO(
q% I
•
% I
–láâƒRò
4i-$c$) (,$c$# 4.
 
c(i-$c$$%
,$c$&# .+
`Cƒ˜{F
$
ŒP܅»–‘’
$
Æȗ,‘’
=
ßàláâoº¹Ÿ—,
$
ìghBW¯d¯
!:r$c$5+
ôˆ‰F‘’lᖿÀÁ•¶·Èӗ,
$
oÆȗ,
*
x%ƒÁÂBÀ
$
?Œ²ç¿ÀÁÂq
ígh
$
Á‡
$
¶·A¬¹’,ëÊx²çu—žÝÞ³´µOC”R¤Ç
$
™ØžŽ_—,
+

yz{
#!
žÝÞ³´µ
,
‘’
,
ßà
,
láâ
,9HMA
ƒ˜

|})(
#!)$53$3)&

~€T
#!
,GHIJK7=8?;0LMNOP
V$&$#!NZ4$4#%
-V
&
WÍÝXYZ

7[WÍ\O
)$&V]$()$$))3$$5#

‚Aƒ
#!
!
!
!
d=>]
!
^_`aef,6X9:=>
!GH@$$$##&$&&344$)!K3.A?@$-[WR-.)$$1Q-M.A?@+,-.

Aƒ„…
#!
4LM
!
gB=>h
!GH@$$&4$&((%!K3.A?@$7?A-A?$&1)#c,-.
;2F,.52F51+/506+.H518515+F/,02D5H52/:> Y,2LN+,-,2L ,2W5F/,02#
+ Q5/+)+2+->8,8068,2L-51+/5
2:$)
$ ]:KZA03.?0X

$ O:9?0X3`TA0
)
$ D2;LO?A037?0

$ O:2F]?0X

!
!c!#$%$&$()*+#%,-#+.,/ % 01%%,+123%,%$ 0/%+ 4,+356()0/%#23%,+17,%,#$ *%8%9 $$%$$$ 0/%+,
)cE/4)%1%+$3 <(#F%$+1$(0/+9,/& ?%@.#%$6()0/%#23%,%$ 0/+9,/& 4$$)$ 0/%+
-@:8/1+F/.!G-C6CMH.AM?,A@6RHd?H*MQH?0,?IH0,HRAMH-WAIdHRCHIRTXRHA,M?-0=HdH0MB6_?0X[A?@?0X?0/H,M?-0c8T,Q IAMABACHCAC
MQHNTB9HI$ K9BACH$ MQH<-,QRA0H@?BRAR6$ <;b:$ U:NDA0aA0XIAMAA0I 4$$)$5cG*-RHd?H*HRC?0IH\H0IH0M@6C,RHH0HI @?MHRAMTRHA,,-RI?0XM-MQH?0,@TC?-0 A0I H7,@TC?-0 ,R?MHR?A$ H7MRA,MHI IAMAA0I ,R-CC3
,QH,[ IAMAcGQH0$ 9HMA3A0A@6C?C*AC\HRW-R.HI B6TC?0XMQH>4c)c$ C-WM*ARH$ CTBXR-T\ CH0C?M?d?M6A0A@6C?C*AC\HRW-R.HI BACHI -0
AXH$ .-IH-W.HI?,?0H$ -BCHRdAM?-0 M?.HA0I RHCHAR,Q `TA@?M6c8?7M63MQRHHCMTI?HC?0d-@d?0X( %(4 \AM?H0MC*?MQ _?0X[A?@?0X?0/H,M?-0
*HRH?0,@TIHI$ 4#% ,ACHC-WAIdHRCHRHA,M?-0C=HdH0MC*HRHRH\-RMHI ?0 M-MA@cGQH?0,?IH0,HRAMH-WAIdHRCHRHA,M?-0 ?0 C[?0 A0I .T,-CA
XR-T\ *AC)i-(5i<:!$c$),$c$4., MQHI?XHCM?dHC6CMH.AIdHRCHRHA,M?-0 *AC#i-(5i<:!$c$5,$c$%., MQH?0/H,M?-0 C?MHAI3
dHRCHRHA,M?-0 *AC&i-(5i<:!$c$),$c$%.c:0 MQHI?XHCM?dHC6CMH.ACMQH.A?0 M6\HC-WAIdHRCHRHA,M?-0C=HdH0MC$ ?0,?IH0,H-W
,Q?@IRH0 A0I AIT@MC*HRH&c#i-$c$) ,$c$(% %. A0I #c(i-$c$54 5,$c$( .$ RHC\H,M?dH@6+2IdHRCHRHA,M?-0CM-C[?0 A0I .T3
,-TC.H.BRA0HIA.AXHACMQH.A?0 \HRW-R.A0,H=HdH0MM6\H$ MQH-BCHRdAM?-0 M?.Hq% IA6CA0I

% IA6C?0,?IH0,H-W4i-$c$) (,
$c$# 4. A0I c(i-$c$$% ,$c$&# .$ RHC\H,M?dH@6c8TBXR-T\ A0A@6C?CCQ-*HI MQAMI?WHRH0MM6\HC-WAIdHRCHRHA,M?-0C$ ,-.B?0A3
M?-0 ?0 MQH?0,?IH0,H-WAIdHRCHRHA,M?-0C=HdH0MC*HRHQ?XQHRMQA0 MQAM-WC?0X@HIRTX$ MQHI?WHRH0,H*ACCMAM?CM?,A@6C?X0?W?,A0M!:r
$c$5cGQ?CCMTI6CTXXHCMHI MQH?0W@TH0,HWA,M-RC-WAIdHRCHRHA,M?-0C-,,TR$ A0I ,@?0?,A@RAM?-0A@IRTXTCH$ CT,Q AC,-.B?0AM?-0$ AXH
A0I -MQHRWA,M-RC$ A0I MQH?0W@TH0,HWA,M-RCdAR6?0 I?WHRH0M\-\T@AM?-0CcGQHRHW-RH$ ,@?0?,A@I-,M-RCW-R,Q?@IRH0 A0I MQHH@IHR@6TCH
/$%%&/
z¨9ƒ
#
žÝÞ³´µ‘’
=
ßàláâ–
9HMA
ƒ˜
C\H,?A@,ARH*ACRH`T?RHI W-RA,@HARA0I -\H0 C\?R?M?0/H,M?-0$ MQH?.\@H.H0MAM?-0 -W?0I?d?ITA@?YHI .HI?,AM?-0c
-_5> R01..!_?0X[A?@?0X?0/H,M?-0, AIdHRCHIRTXRHA,M?-0, AIdHRCHIRTXHdH0M, ?0,?IH0,HRAMH, 9HMA3A0A@6C?C
.0,#!& %`TZDFWF**&!#%!&
!!
žÝÞ³´µ
!
iüžÝÞ

Hí*‹Å
–¸[ŒˆÚ–[r¥$,ùÿÚÔ
$
ÈNW
*
׍
;
!
X
*
æç*
ès
*
m*ñ
!
X
*
ŽO
*
‹
{l ÁšWC›
+
@BžR¡Ò
*
_h@û
*

Ýꖙš
,
—¹Rª
*
Ñë
*
$ñVì
*
Ñzž
,
¶·—¹ò€³Õ
*
ŒÎ’523
*
ñÕ
*
‚Ï#ê
›
*
‚0ό@¥ô
+
ô,~Ä`B³´µ U
IX
)
rê©
+
žÝÞ¹
(%4
x’—¶·
$
é¹
(()
x
)
yÆ%]$A,½ÓnÛ ò
(
v%$
AA£ò€&
!
7

kÝj…$›,àB
)
-.
+
¹
)$$
x

y
$
%],~‘’¤¥$Skœj
©žÝÞ³´µpÖÕ֑’
-).
$
[ª•«BÀ
–‘’
!AIdHRCHIRTXRHA,M?-0$ 2J>
 ß
à
!AIdHRCHHdH0M$ 2K
j5<ß¹A|k
+
%
]§~,~¤¤½ÓtnDs–
(
%],~‘’
¤¥xHj©
!)$&
x
)
${F
$
žÝÞ³´µ¹
)$$(
xs
)$&
xZÓ
5
xò$›,³´µ
2J>=2K
j©=Øeúâ

·–~r
-4.
+
ȇm
$
žÝÞ³
´µíÔþ¼UbB–u8.¸
$
Á‡
$
À³žÝÞ
³´µ–‘’í¶·Œ`ò.`
+
,xÿ
$
j5žÝÞ³´µ‘’–¿Àˆ
‰ÿ_
$
Z1ƒˆ‰qíLÞØV:
$
?q툉ÿ
!
*
ˆ‰²ç
*
ÎÏO(ƒ‹{gh
$
j©–‘
’láâƒ)±ghÿº
$
óc‘[žÝÞ³´µ
‘’lᖙomÉëì0.1H
+
ވ‰v
—õWÉ~ 
9HMA
ƒ˜ÿ!
$
¬žÝÞ³´µ—,
ô
2J>=2K
láâ5mÇȃ˜
$
_0[ž¸¹ÿ
ºLÞؖžÝÞ
2J>=2K
láâ°ÙO
$
c|ò
¶·ADz¹ë¿À17y2žÝÞ³´µ
2J>=
2K$
òÝ6¿À> Ùڏ:ö&Ÿ‚
+
!M
¯°•ÿ!
!a!M
ÂA•efœ
!a!a!M
ˆ‰…»
!
=¸¬­\è
!>ª«¬­
ˆ‰
*
d鈉
*
Îπˆ‰
+
^rC$
*
ï^
+
!a!aM
ˆ‰¬b
!
žÝÞ³´µ—,óô
$
C€
R
*
x%
*
‚ªr…
+
!a!aSM
I×Ø
!
Ÿ(u—žÝÞ³´µ(ä
!
Ÿ ³´ÔëUIX
$
~•ìÜ,öƗ
+
!a!a%M
)nۜ
!
j©%‘’
=
ßàláâ~
ömW¯‘’
=
ßàláâ–=‚
+
!a!a#M
efœ
!
(.ùlP~Œ[$Sˆ‰
$
ë
¢v^cuh.ù–:ºLÞؖ^Ä
,
)Ç@
~@É
,
*uBxÑ
$
h!^ŽUC=‚–^Ä
+
!aM
›‡³Ð
¯d¸›‡
NTB9HI$K9BACH$MQH<-,QRA0H@?3
BRAR6$<;b:$U:N$DA0aA0XJAMA
 
›‡OC
ò‹«O(s
)$5
x
%
y
4$
z
+
v—Ä6ð ¹
Èð¿)Ȗÿ©5m›‡
+
$^›‡ðŸ žÝ
Þ
*
6:—
*
v€
*
‘’
*
ßà
,
ï^›‡
ðŸ 
_?0X[A?@?0X?0/H,M?-0$C?IHHWH,M$AIdHRCH$CAWH3
M6$M-@HRAB?@?M6+
c
NTB9HI
ò«
$
@Ž›‡³Ðò
t
_?0X[A?@?0X?0/H,M?-0, t) C?IHHWH,MF>AIdHRCHF>
CAWHM6,t4 t 2;Jt)+
!aSM
^Ävc
*
¯°Ž•×ØÉ~
È
)
·ˆ‰ôO‚Âeœ(9vc^Ä
*

Ž¯°ë×ØÉ~é«Îõ¬
$
o@Ĕ
$
«Èâ
4
·ˆ‰ôï?
+
kLë¢^6 Ç`5m´v
$
e
f‹{ÁÈÂAœ–^č
$
¬m¤ÁÈÂA
œ–^Ä5[+ë¢v^5mùv
$
c¥ HU
ÂA
+

K7,H@
xà‹9¯°ŽP
$
@ŽŽ
–8;Ÿ :ôuB
*
lPxp
*
ˆ‰…»
*
LÞØ
*
×ØÉ~
*
FJ
*
Éo
=
$·x%
*
ÎÏO(
*
ÔØ
*
—
,ÿ© ¬­,ö–úü
+
ÂAˆ‰–
>ÿ!
×Øv—
<-,QRA0H
õWÉ~¹JS
5cc$
–V
WñçÉÊ
-&.
@5m×ØÉ~
+
Ÿ 
%
žjà
$
{žjàÁȯò

ƒ
$
tƒ$
&
ƒyò^Ä×
Øÿº
+
¬¹Îπˆ‰
!
d鈉 ª«¬­ˆ
‰

´æ
9FF8K
Û9
-5.
5m×ØɃ
+
Ƀjà
Ÿ 
#
(ž°‹¥F×@ˆ‰–Mù~à–
,
)ˆ‰
¬bHUB‹¥–ÂAefœ
,
*(äÿ¨HU
B)͖×@
,
+¬¥Ø–)n“0‹¥–€~
 ¯
,
,HUßLʯLÞØ
$
¥×@óôHZÓ
¼Ì–
,
.ž°‹¥×@ˆ‰Ä`lÜ
$
=îۜÉ
~ëÎ
,
/W¯ƒ˜BS
$
t)n5mƒ…ƒ˜ëj
©
$
on­‚ªƒ|
*
_è)±hw
*
óô–”£ƒ
+
{žjàÁȯò

ƒ
$
tƒ$
&
ƒyò^Ä×
/%%&/
)$5
x
)
y â
&$
ãâ
)&
|
U-@c&$$ ;-+)& JH,H.BHR$ )$5
Øÿº
+
¬¹Îπˆ‰
!
d鈉 ª«¬­ˆ
‰

´æ
9FF8K
Û95m×ØɃ
$
oŸ 
%
žj
à
$
)^Ä
-5.$
{žjàÁȯò

ƒ
$
tƒ$
&
ƒyò^Ä×Øÿº
+
šØãÐm¤,á–V
W
$
lh!ãÐÝ5mÖ2€ƒ˜
+
!a%M
W¯ƒ˜

>4c)c$
xà5m
9HMA
ƒ˜
+
ȹwˆ
‰«(qíÿºh׀
$
ðv—=¸š’å»5m
‘’
=
ßàláâ–=‚Èé
$
é¯d
(5i
m
uJ(
!<:$

E-.-XH0H?M6MHCM!G
ݏ

5m[
b€›è
!
›èmò!
h$c$
ŒO)È
!
)
 ØÑ
[b€–º:
+
5[+n­ˆ‰²ç
*
—,ÿ©
 ÎÏO(ƒR5m`Cƒ˜
$
šØí0h׀ÿ
>
$
—$
)
›èÉÊ`C(–gh
+
v—Qñpƒ˜
 
KXXHR
ݏʯݴlPVW
$
é@ÕÖ2€ƒ
˜É~ôˆ‰)±–% €
-#.
+
M

a!M
^ě‡)±
´›0¿À^Ä
) #$#
å
$
kLt›‡þ–^
ÄÌA
;-MHK7\RHCC
5m^ĽÓ
$
òf.ù^Ä
($)
å
,
ó/
%$&
å^Äë¢^[6àëÇ`
$
O
‚ÂAëefœ:=ÂAƒ˜–B
#4
å
+

vc¼1ë)±p
+
p
!
^Ävc¼1ë)±
a?Xc!a@-*,QARM-WCMTI6CH@H,M?-0
aM
ÂAˆ‰–¸Þ”£
#4
å^Ė¸Þ”£P
+
ވ‰ÂA^Ä
n­ˆ‰…»ƒ
#>ò
5)
å
$
É=¸¬­\è
%
å
$
ìÜÎπˆ‰
&
å
+ #4
å^ÄtÂAˆ‰¬
b
& $(
«
$
ì$
( %(4
«òžÝÞ³´µ—,ô
$
ê¯lá
4#%
«žÝÞ³´µ‘’
=
ßà
+

Œˆ‰(LÞØghÿº
$
ì$:]ôò
4$
«
-%.
$
:_ôò
4 $#$
«
-.
,#
å^Äj©%x%$·=
*
Éo=~j©ý-
$
ý-ºÜí
)
žy
p%#
*
,)$
å^Äj©òŸ—,
,
—,ÔØò
# p$ .O+
ì$

å^Äj©×ØɃ$
&
ƒòº×؈‰
$4%
žò“×Ø
$
Éo×Ø_ƒò
)c
ƒ
+
ވ‰ÂA
–
5)
å
>$
$
B
4%
å^Ä}ë
&


){
$
b×@@Ž–=¸ÿ!
$
å^Äj5%HUv—
ƒÍœÐ
$
B

å^Äu—Êô
+
žÝÞ³´µ‘’
=
ßà2ˆ…»P
)+
t
4#%
«‘’
=
ßàn^Ä×@–”•ƒò÷
» .»
#
ì$÷»‘’
=
ßàÝ
(&c#i!4&%=
4#%$
.»‘’
=
ßàÝ
5c&i!)$=4#%+
ì$
÷»‘’
=
ßàc©Oë,*2ˆòÄ
$

ú
*
./
*
l’:ò_
4&c#i!)$=4&%$
ìœH
K_õW
2J>=2K
Ý
)5c#i!#(=4&%$
³´1·
2J>=2K
Ý
&c&i!5$=4&%
ƒ
+
aSM
žÝÞ³´µ‘’
=
ßàláâ–
9HMA
ƒ˜
ވ‰cu‘’
=
ßà2ˆ…»j5:_
–
4
žPÜ5mláâ–
9HMA
ƒ˜
$
ì$m©Oë
,*‘’
=
ßà–^ÄB
4$
å
$
j©%
4
žÿ
ð–©Oë,*–2ˆ
$
Ÿ ©ú
*
./
*

!
0
’
+
tÂAžÝÞ³´µ—,óô
& )54
«
$
êø

)$
«©Oë,*2ˆ
,
K_õW‘’
=
ß
à^Äò
4$
å
$
j©%
4
žÿð–K_õW‘
’
=
ßà
$
Ÿ @S
*
ü
!
å
*
”„
*
”Ú
!)
å
*
A€Yyº
!#
å
+
tÂAžÝÞ³´µ—,
óô
(#5
«
$
êølá
(
«K_õW
2J>=2K,
³´1·–‘’
=
ßàò

å
$
j©Ä`PÜ
òn1Ͻƒ„
+
tÂAžÝÞ³´µ—,óô
4)(
«
$
êølá
5$
«
2J>=2K+
¬
4
ž…»
‘’
=
ßàláâ5mÉÊ
$
{Fˆ‰)±(qí
ºH–h׀
!!
)
q$i$:r$c$$$ $9HMA
ƒ˜)
±òžÝÞ³´µ©Oë,*‘’
=
ßàlá
â
4i-(5i<:!$c$),$c$&.,
K_õW‘’
=
/)%%&/
z¨9ƒ
#
žÝÞ³´µ‘’
=
ßàláâ–
9HMA
ƒ˜
!!
/4%%&/
)$5
x
)
y â
&$
ãâ
)&
|
U-@c&$$ ;-+)& JH,H.BHR$ )$5
/&%%&/
z¨9ƒ
#
žÝÞ³´µ‘’
=
ßàláâ–
9HMA
ƒ˜
P
)!
žÝÞ³´µ
2J>=2K
2ˆ…»
GAB@H)!_?0X[A?@?0X?0/H,M?-0 2J>=2KIA.AXHM6\HC
2J>=2K
…» ×@
2J>=2K
l᫜ Š›n
=i
÷»
2J>=2K 4&%
!
©Oë,*
2J>=2K-
©ú
*
./
*

)$ 4&c#!)$=4&%
!

.
!
K_õW
2J>=2K!
@S
*
ü
*
”„
* ( )5c#!#(=4&%
”Ú
*
A€Yyº

³´1·
2J>=2K!
n1Ͻƒ„
5$ &c&!5$=4&%
,öR
!
lR
*
ºô
*
ûõ
&) )c!&)=4&%
쵛W
-
<Í1$]
!r4c$u$
(
=O.
)c4!=4&%
!
ΒõW
!
ØÙ
*

*

*
g~
*
K
ý
*



#
)c4!=4&%
c%!=4&%
ìÜ
!
‡Ž†õ
2J>*
Ÿ/ƒ
)& #c(!=4&%

2J>=2K )$
Õր?!
Õր?\Û|PÜ
) #$c$!)=)$
Agm/
&$c$!)=)$
ßàláâò
#i-(5i<:!$c$5,$c$%.,
³´1·
‘’
=
ßàláâò
5i - (5i <:! $c$),
$c$.+
öfÖ2Hÿº^č5m
9HMA
ƒ˜
$
{Fˆ‰)±(Œ×
!!
)

5$i$:
$
$c$$
v—v
 š’å»5m
9HMA
ƒ˜
$
)±{FžÝÞ³´µ
©Oë,*‘’
=
ßàláâ
)i -(5i<:
!$c$),$c$4.,
K_õW‘’
=
ßàláâò
#i-(5i<:!$c$5,$c$%.,
³´1·‘’
=
ß
àláâò
&i-(5i<:!$c$),$c$%.$
ðv—Ö2
€ƒ˜=‚
$
p
) p5+
a%M
`Cƒ˜
ȹ³´1·‘’
=
ßàh׀ÿº
$

cu%
)
žÆj5:_–‘’
=
ßà…»
#
©O
ë,*–‘’
=
ßà K_õW‘’
=
ß
à
+
}ÙqB¬­–ˆ‰
$
íЬ­C
+
Ütˆ‰
!!
p
)!
©Oë,*‘’
=
ßàláâ
9HMA
ƒ˜
a?Xc)!9HMA3A0A@6C?C-WMQH?0,?IH0,H-WC[?0 A0I .T,-CA2J>=2K
n­—,ÿ©
*
ˆ‰²ç ÎÏO(5mláâ–
Èéëì`Cƒ˜
+
)±{FhÛc©Oë,*
‘’
=
ßà
$
ÞHcK_õW‘’
=
ßà
$
ÆÈ
—,‘’
=
ßàláâoº¹Ÿ—,
$
ìghB
W¯d¯
!:r$c$5+
a%a!M
©Oë,*‘’
=
ßà–`Cƒ˜
!
Â
A
)#
å^Ä
$
ȯ
4 44$
«žÝÞ³´µ—,ôl
á
$
«©Oë,*–‘’
=
ßà
$9HMA
ƒ˜)
/5%%&/
)$5
x
)
y â
&$
ãâ
)&
|
U-@c&$$ ;-+)& JH,H.BHR$ )$5
!!
p
4!
K_õW‘’
=
ßàláâ
9HMA
ƒ˜
a?Xc4!9HMA3A0A@6C?C-WMQH?0,?IH0,H-WI?XHCM?dHC6CMH.2J>=2K
p
&!
³´1·‘’
=
ßàláâ
9HMA
ƒ˜
a?Xc&!9HMA3A0A@6C?C-WMQH?0,?IH0,H-WAMMQH?0/H,M?-0 C?MH2J>=2K
/#%%&/
z¨9ƒ
#
žÝÞ³´µ‘’
=
ßàláâ–
9HMA
ƒ˜
p
5!
K_õW‘’Qñp
a?Xc5!GQHWT00H@W?XTRH-WI?XHCM?dHC6CMH.AIdHRCHRHA,M?-0C
±{F
#
Æȗ,
*
’,
*
—,O(
% I
–žÝÞ
³´µ—,²ç–©Oë,*2ˆláâÿº
$
@
Õ$
)
ݏ
$
Fw`C«(©Oë,*
2J>=2K
l
áâghhW¯d¯
$
P
4+
P
4!
©Oë,*
2J>=2K
Œ`C(láâ–
9HMA
ƒ˜
GAB@H4!9HMA3A0A@6C?C-W?0,?IH0,HBHM*HH0 I?WHRH0MCTBXR-T\C
-WC[?0 A0I .T,-CA2J>=2K
`C
ƒ˜
ˆ‰
=
ê{
lá=
ê{
LÞØ
Èéláâ
-i!(5i<:.
h׀
!
)
:
Ÿ—,
! $ &% #( $c$)( -$c$$ 4,$c$%( 4. (c4 r$c$$$
Æȗ,
# 44 #& $c$4& -$c$)& ,$c$& #. &%c r$c$$$
’,
!! & )5 4&( $c$)( %-$c$)$ ,$c$&4 %. ))c5 $c)$(
›²
!! $ &% %5 $c$)) 5-$c$$% &,$c$## . ($c) r$c$$$
bj©
! ) (# $c$& 4-$c$)$ ,$c$$ 5. $ $c#4& )

% I! ( # (& $c$4$ $-$c$) (,$c$# 4. %c4 r$c$$$
q% I! % ( 4( $c$( )-$c$$% ,$c$&# . #(c5 $c$$4
a%aM
K_õW‘’
=
ßà–`Cƒ˜
!
ÂA
)(
å^Ä
$
ȯ
#(
«žÝÞ³´µ—,ôlá
%
«©Oë,*–‘’
=
ßà
$9HMA
ƒ˜)±
{F
#
Æȗ,
*
›²
*
—,O(
q% I
–žÝÞ³
´µ—,²ç–K_õW
2J>=2K
láâÿº
$
@
Õ$
)
ݏ
$
Fw`C«(©Oë,*
2J>=2K
l
áâghhW¯d¯
$
P
&+
a#M
lPVWëÖ2€ƒ˜
¬Œ…»‘’
=
ßàláâ–^Äv—
KXXHR
Qñpƒ˜ìlPVW
$KXXHReMHCM
{F
$
lP
VWhW¯d¯
+
tÖ2H
=
”hHÿº~ÿ“
–^Äöf5mÖ2€ƒ˜
$
)±ø_ÿº
+
5
mÖ2€ƒ˜¼
$
žÝÞ³´µ©Oë,*‘
!!
P
&!
K_õW
2J>=2K
Œ`C(láâ–
9HMA
ƒ˜
GAB@H&!9HMA3A0A@6C?C-W?0,?IH0,HBHM*HH0 I?WHRH0MCTBXR-T\C
-WI?XHCM?dHC6CMH.2J>=2K
`C
ƒ˜
ˆ‰
=
ê{
lá=
ê{
LÞØ
Èéláâ
-i!(5i<:.
h׀
!
)
:
Ÿ—,
! % )% 5%& $c$5) -$c$)) $,$c) ). %%c% $c$$$ )
Æȗ,
)) #$ )(5 $c$#4 $-$c$&( ,$c$$ 5. 4(c( $c$) 5
’,
!! ( 4 %4( $c$&# -$c$) ,$c$(% %. %5c r$c$$$
›²
!! 5& (%% $c$#( 5-$c$54 5,$c$( . )(c5 $c#
bj©
! ) ) 54 $c$4 %-$c$$4 &,$c$54 ). $ $c#5 4

% I! 4 &4 () $c$5 -$c$)( ),$c$($ . #(c $c$$$
q% I! # && (& $c$5# -$c$45 (,$c$ #. 55c4 $c$$4 (
’
=
ßàláâ
4i-(5i<:!$c$),$c$&.,
K_õ
W‘’
=
ßàláâò
#i - (5i<:! $c$5,
$c$%.,
³´1·‘’
=
ßàláâò
5i
-(5i<:!$c$),$c$.$
ðv—Ö2€ƒ˜ÿ%
 =‚
+
SM
Û
Sa!M
žÝÞ³´µ
2J>=2K
lá▃˜
ވ‰ÂA
#4
å^Ä
$
t
( %(4
«žÝÞ³´
µ—,ô©Oë,*2ˆ
*
K_õW
*
³´1·
‘’
=
ßà–láâƒRò
)i$#i$&i+
Vf

-.
í
)$$%
xlP–[ºˆ‰)±P‹
#
‘
’cÕ֑’láâ:º
!c)i$
ìœòK_õ
W‘’
!ci
 Ï½º¸‘’
!$c$i+
ވ
‰)±{FŒ…»‘’láâoB‹{y
º
+
ZO_³d–H
$
ވ‰‘’lá▯
dÿ©•Vf–ˆ‰j5qígh
$
ވ‰
‘’láâH@Õ
9HMA
ƒ˜ÿ!5m¯d
$
(Vf
Hn­‘’lá«=•—,²ç–Š›n5
m¯d
+
ŒO
$
Á_þžÝÞ³´µ–u—tØ

$
ވ‰}¤W¯DÝlP–
2J>=2K
«= 
lPßàt«=–¿¬¿ƒâ
+
SaM
žÝÞ³´µ
2J>=2K
àláâ`Cƒ˜
À¹žÝÞ³´µ,ö‘’,á®Á•l
átu–†[6H¶·AáÀ³–Rî
$
ì®Á
ëlátužbƁ™
+

-).
–[ºDE€ˆ
‰)±{F
$2J>
láâ•óôx%
*
€R
*
—,Ô
Ø
*
Æȗ,ƒBÀ
+
‹fƒ
-4.
í
)$$
xlP
–[åDE€‘’j©${F
$2J>
mlá¹
8úx%
$
cø_’ ’,láâ:º
+
(+ù
ƒ
-&.
ˆ‰F
$
žÝÞ³´µ‘’–lᕀ
/%%%&/
)$5
x
)
y â
&$
ãâ
)&
|
U-@c&$$ ;-+)& JH,H.BHR$ )$5
Rx%hÀ
+
ވ‰`Cƒ˜)±{F
#
í©Oë
,*2ˆ‘’…»$
$
Æȗ,
*
’,
*
—,O
(
% I
–žÝÞ³´µ
2J>
láâÿº
,
(íK
_õW‘’…»$
$
Æȗ,
*
›²
*
—,O
(
q% I
–žÝÞ³´µ
2J>
láâÿº
+
ȇm
$
‘’,á®ÁHU•óôx%

$
ވ‰F¬¹Œ–‘’…»ÿù
$
’
, ›²–
2J>
láâqígh
+
íc©Oë,
*2ˆòÄ`Pܖ‘’…»$
$
’,láâ
º¹›²
$
Ä`HÁò’,O|wC^Èə¤ë
YõW
*
ÐÑõWžb¹v
-5.
$
¬,ö–’“
*
P
E
*
eR¤èg
$
¬­%
2J>
–láâ
,
(cK_õ
WòÄ`Pܖ‘’…»$
$
›²lá⺹
›²
$
ì$cÊx²g_
$
m¤•Êx²óB_r‚
ª
$
—,¸+º¹ìܲç
$
쪔ù-
$
[Žqí
_,Œ—
*
.ù—,ƒ™o56BÀ
+
„†
$
Êx²
ȹáÓ¸¤÷+lÑ
$
K_õW™¤Tl
$
,P
Åèláyø
$
¬,öPE•úÔ¤èt“
$
.b
2J>
láâŒy
+
Á‡
$
¬¹’,ëÊx²çu—
žÝÞ³´µOC”R¤Ç
$
™ØžŽ_—,
+
â9ûƒ
-#.
lÜÆȗ,H.b
2J>
láâ
¬­–œó«[
$
•Þˆ‰)±¿Ò
+
ވ‰`C
ƒ˜)±{F
#
폌P܅»–‘’$
$
ÆÈ
—,láâoº¹Ÿ—,
$
ìghBW¯d¯
!:r$c$5+
žÝÞ³´µUm›ƒ¿Sù-
$
w
,ö«(–¿ª:—žxvž°
$
ì$[ª›ƒ
sÔW‘Hø_–¿À0Ü}¡Hæt~,á|È
ö0ÜæI(lá
2J>+
BÀžÝÞ³´µÍÓ
—,–¶·ë™è=‚žwF
$
@Ž)±B[™
è–5[+聠¶·5[+ÎÏ
+
SaSM
ވ‰qí–éꕏF
༺ؖ¶·ˆ‰
$
wwȹ#
*
()jà
–CÚ
$
ˆ‰–LÞ«=Õ]
$
.b›èš¤t“
+
m¤0Ü[ªŒ…»–ˆ‰
$
*^_[b–)±
$
ƒ˜É~Mªˆ‰)±O
$
mÙq
9HMA
ƒ˜
$

 Ø–?tƒ˜
$
º›èš¤
$
í(B†¹lÜ:
聂
-%.
+
Þ^¬žÝÞ³´µ$lP–^Ä5
mwƒ–›‡
$
ÿòvð–ÂA%_ºˆ‰
$
•Ÿž
®Iˆ‰¿n
$
ºº¬­%LÞØ
$
ŒOü\—
9H3
MA
ƒ˜ÿ!¬ì‘’láâ­cÉ~
$
é@Õ
`Cƒ˜†‘’lᖿÀ.çÁÂ
+
Z
`_0FBùè–)Û
$
ވ‰ÞqíF«v
#
(ÂA–
>×Øÿ“
$
º_=ˆ‰}þ
&


){
$
?ä_.`uBý±
$
†¹
2J>=2K
–®
Áƒ˜
,
)Á_þžÝÞ³´µ–u—tØ=‚
$
ވ‰}¤W¯DÝlP–
2J>=2K
«= lP
ßàt«=–¿¬¿ƒâ
+

ˆ‰?Š
#
- .!
%]$A,½ÓnA6E
c
v%$AA£ò€&
!
7


j…$›,’—Û9
-8.c
23
#
$%A,0‰&
$((4#)c
- ) .!
%],~‘’¤¥$S
$
%]§~,~¤¤½Ón,~
É~$S
c
öþžÝÞ³´Ô0.‘’
-S.c
$%û¨

$)$$($#!5#))c
- 4 .!
%]§~,~¤¤½Ótn
c
%],~‘’¤¥xHj©
!)$& -KP=FO.+-)$53$%3%.+QM\#==***+CIA+X-d+,0=
D8$=- & .!E?XX?0CSNG$ 2@M.A0 JL$ 8MHR0HS2<+R?C[ -WB?AC?0 ?0,@TIHI CMTI?HC$,-,QRA0HQA0IB--[ W-RC6CMH.AM?,
RHd?H*C-W?0MHRdH0M?-0CdHRC?-0 5++$ -KP=FO.+!)$3$43
)+-)$43$3$.+QM\#==QA0IB--[+,-,QRA0H+-RX+
- 5 .!8MR-T\ Ja$ PHR@?0 S2$ 9-RM-0 8 <$ HMA@c9HMA3A0A@6C?C-W-B3
CHRdAM?-0A@CMTI?HC?0 H\?IH.?-@-X6-S. cS292$ )$$$$ )4
!5# )$$c
- # .!
^z9
$
ÿ’õ
$

$
ƒ
c
í
>
xà$™ÜŸžâ–
9HMA
ƒ˜
-S.c
æA
$)$4$4!4#c
- % .!
!¨Ï
c
$›,XÛ(äªÒ€SPՖäšë‘’
-S.c
$%™—A,
$ )$4$!4&#%c
- .!
ÅÆÇ
$
ˆÄ
$
Eìí
c
žÝÞ³´µÕÖóôϞÐє
_<ëÍ1Ásø_tu–¶·ˆ‰
-S.c
$%$,-.
$
)$$ 4#!$# 4)c
- ( .!
þ¨$A£¾ËA£
c
FºNžÝÞ³´µ(ä$ñª
«º¶·è–ÎÏj©
-<.c
23
#
v%$A,S‚ª$
,—,¶·É~ˆ+
$((c
-$.!
23$A,º567A£
+
‰2җ4²&A£
c
ºN
žÝÞ³´µ(äò€$ñªL|¶·è
-<.+
23
#
v
%$A,S‚ª$,—,¶·É~ˆ+
$((c
-.!
Vf
$
¨’;
$

c
žÝÞ³´Ô‘’^ÄõWÉ
~
-S.c
$%,¨
$)$$%$#!)$c
-).!

c
«žÝÞ³´µ–‘’ƒ˜
-S.c
$A$,
$
)$)$)$!(# 4)c
-4.!
‹f
$
1™(
$
$†%
$
ƒ
c)
«žÝÞ³´µ‘’
j©ƒ˜
-S.c
$%,ööw
$)$$$%!)##c
-&.!

$
Ÿ&
$
T
c
žÝÞ³´µb‘’
44
«^ă˜
-S.c
$A,¶·-.
$)$)$)&!#%)4c
-5.!
Œ(¥
$
)½*
c
—£7€’&—,”•ƒ˜
-S.c
$%,ö
öw
$)$$($#!5#)(5c
-#.!
â9û
c
žÝÞ³´µb‘’
$&
«ƒ˜
-S.c
$%,
Ñ
$ )$)$)4!)&# ))%#c
-%.!
]
$
¤[¿
+
æA
-9.+
23
#
²&¸á0‰&
$
)$$5##$c

‹Œ-0
!
ŽŽ
#
/%%&/