免费文献传递   相关文献

Chemical constituents from the roots of Pithecellobium lucidum and their cytotoxic activity

亮叶围涎树根的化学成分及其肿瘤细胞毒活性研究



全 文 :œEžŸê[\]Ú6Gª ¡¢£¤T›ƒ„
ɲè
#
Äcà
#
o³´
#
.×&
!
#
\%·
!
8;H¯I¯J ëìíîH¯J KñLMN
#
š1KñNOñ&*
ØP;Ç?H!#
#
ëì
PMMMLM
$
…;
%!

&
ƒ„œEžŸê[\]Ú6GªQ ¡T›

š›
.
\›è¬
!1(U#$5(KB.;WM!.8B
‡¿ {ˆ÷Ñ
vÉ6›{!
›
><3
‡ˆ]…”6‹/Ô\ÄÌ01


<@@
”A6›&Œ[\ÄÌvÉQ ¡T›¯#

œ
.
±
œEžŸê[
_Lh
|½µ#Ì[|@|]×#Ìr6›&Œ
X
\ÄÌ
!
6JÕÔê
.H4&c%/05(=
W
$!%!O;$W;$G(2$I5/;
W;5(/KA;
#
6@;*&4G/UA%$)/0A&%/KA(;PX

;#A5%/KA/&($);PW;();WN;/G$G5$#%!
p¾L@
$$%!
p¾L@|]
$%%!$ j%;
-§—
$&%!
$ Q%;
p¾L-§—p¾L@]
$%
\ÄÌ
#
A±¬ ¡¢£
=W[NM
wèR=[¢£¤T›
$:
LM
P [`W
!
I/&/B
QP
%
œt
.
\ÄÌ
! `
Œêp5±aÉÌr6›¨&

\ÄÌ
#
A±¬ ¡¢£
=W[NM
wè.u[¢£¤T›

$
†‡ˆ
%!
§ê*W
&
œEžŸ
&
ƒBÇh
&
MC
&
¢£¤T›
$
8‰$f
%!WMPPMOPLMML
$
Š‹Eq
%!
­æ&Kf÷stuv
$OMXWLM^M%&
ö÷Øi‚ŠÇ
ÁÜuv
$WMM_d+M_OPP;MM^%
$
Œƒ>
%!
!

!@(&.$MPM% XOPXLOWX!J$K.$MPM% XOMP[[L[!
-;I$&.A40#0#$)\II`$G`G)
!!
œEžŸ
?/!2$)$.&=/3.3)/137()2#!
”P
œE§ê*
#
(Qó
!
ê²ö§ê*WÉÌ
!
6ʝ
򭀬
#
.Y
#
í)
#

#
–Â
#
Áý‡Q

õE
ÐÇ
!
è6¤
!
‚é*ä
#
=yb
#
âŠãä
P(

§
ê*W
?/!2$)$.&=/3<$%2
ÉÌWZ+@«ö
!
O
ŽoI
PMM
 
!
6ʝ¸†«SÑAS
!
ò­è
^
 
!
6Jû§ê*
?` ).(%$0#/0!
Ç,²
?` 13.)$!
œ
E§ê*
?` .3)/13!
œEÇ,²
?` =/-$/3
W(

A§ê*WÉÌ[\]ƒ„¼.
!
aWÉÌrZè
™ \]Ú6
!
ªã¥T›6‡
!
w袣¤
#
љ
#

#
8b
#
QE¤‡E›
^;X(

h•ƒ„NErÏ
±ªê[
_Lh
|½µ#Ì[»V½ØI6›&Œ
O
Š[wè ¡¢£¤T›[01j£[ƒBÇ
h
[(

¤ƒ„1:±ªê[
_Lh
|½µ#Ì[|
@|]×#ØI6›&Œ
X
\ÄÌ

6JÕÔê
H4&c%/05(=
W
$!%!O;$W;$G(2$I5/;W;5(/KA;
#
6@;*&4;
G/UA%$)/0A&%/KA(;PX

;#A5%/KA/&($);PW;();WN;/G$G5
$#%!
p¾L@
$$%!
p¾L@|]
$%%!$ j%;

—
$&%!$ Q%;
p¾L-§—p¾L@]
$%
_
\Ä̌êp5±aÉÌr6›¨&
!
ªr\ÄÌ
#
A±¬ ¡¢£
=W[NM
wè.u[¢£¤T›
$:
LM
P [`W
!
I/&/B
QP
%
!
ßàiÁÂ
<(%G4%A;^MM
*öÐ6ß
!
ÌÛkê~À
&=*;
&()2PPMM 1(%(0B;<1R;@%$U;1B
âYˆß%Ô
-1:;
<1&B;X=R
¡Uj{ˆß
!
ÜÝâmj
f<;
8$GV TR1;=
{ˆ-
$WM IInWLM II!L
!
I%&1(U#;
$5(KB.;WM
ê¿Ò
=I(%0#$I8#$%I$G$
–$ãä
&
-{ˆè¬
$PXM iWMM
v
!WMM iOMM
v
%
Ñ:4{
ˆè¬
?JWL^
Œêf¡&—\Nåäï

§¨ÇÁ
WMM^
÷
_
²0l6)
!
G6)rþ
]‘Ä¥s<=ÕÔêœEžŸ
?`.3)/13
[
ê
!
À¤AŒr­þ]ö]‘Ç̃„²À¤É
$
À¤f
>/` _MWPP%
#
µ#6›
#Ÿæ[œEžŸê
^ L` V*!
34
!
›
_Lh
|½yÎ
O #
¾
!
a¸Ètµ#
O
5
!
µ#QM<
¢&Œ
^_M *

!
Vª6ϝOr
!
¦5›|@|
]ÑO~Ñ»V½×#

¿×#6JQM<¢
!
&|@|]×#Ì
PML *!
»V½×#Ì
OPM *
#
|@|]×#Ì
PMM *!
ˑZÔ-{ˆ
!

_Mh
|
½ÈÍ
!
&Œ|@|]ØI¼ï
^L *
#a¼ï
^^
*!
Ëè¬-{ˆ
!
Åì
;

$WMqP iPqP%

Í
!

_
Ù6
$J%`P i_% J%`P
ÖËè¬-{
ˆ6›&Œ\ÄÌ
$$PM I*%
Ñ
%$PW I*%&J%`W
Ë
1(U#$5(KB.;WM
-{ˆ
$
g½ÈÍ
%
&Œ\ÄÌ
&
$W^M I*%&J%`^
Z‘Ë
1(U#$5(KB.;WM
-{ˆ
$
g
½ÈÍ
%
&Œ\ÄÌ
#$NM I*%
Ñ
$[ I*%&J%`[
Ø
/_X[P/
{
OX
ï{
PO
•
WMPP
÷
[
²
!!!!!! ! ! ! ! ! !!!! ! ! ! !
S/&`OX! :004(!PO
94&A! WMPP
mjË
1(U#$5(KB.;WM
-{ˆ{!
֏Ü݁j

$
|g
;
O
OMh%
&Œ\ÄÌ
!$PL I*%
$
01ÕÔ
\ÄÌ
!
t{3H
!Bc(%I$));74%G#$%5

m\Œê1›

P
.;><3$ UA%5)(;1
L
!^MM
<.a%
!
.M N`M!M N`^!M N`[!P M`W! P M`O! P O`L! P`^P
$($G#!O.!0!2(%2I(2#A&%!P`^N $O.!5!UYX L` .a!
J4G;X%!^ _`O $P.!5!UYN L` .a!?&G;P%!L M`W $P.!
5!UYN M` .a!J4G;P%!L M`X $P.!5!UY[ M` .a!KA&;
P%&
PO
;><3$UA%5)(;1
L
!PMM <.a%
!
. ON [` $;P%!
WX N` $;W%!N[ _` $;O%!O_ X` $;^%!LL _` $;L%!
PN`^ $;X%!OW L` $;[%!^M`^ $;N%!^[ O` $;_%!
OX _` $;PM%!WO N` $;PP%!PW^ L` $;PW%!P^M P`
$;PO%!^O O` $;P^%!ON W` $;PL%!XX [` $;PX%!
LM M` $;P[%!^P [` $;PN%!^W N` $;P_%!O^ P` $;
WM%!NO`^ $;WP%!W[ P` $;WW%!WN L` $;WO%!PL N`
$;W^%!PX O` $;WL%!P[ M` $;WX%!WN P` $;W[%!
PNP O` $;WN%!WN _` $;W_%!W^ W` $;OM%!PMX [`
$?&G!;Pg%![L N` $;Wg%![N`^ $;Og%![P [` $;
^g%![X _` $;Lg%![M M` $;Xg%!PMO`^ $J4G!;Pw%!
NW O` $;Ww%![L W` $;Ow%![W W` $;^w%![P [` $;
Lw%!P[ W` $;Xw%!PM[ M` $+A&;Pgw%![L _` $;Wgw%!
[[ L` $;Ogw%![M N` $;^gw%!X[ W` $;Lgw%
_(
)i7«
N(
1:[()|Ì
!
ÕÕÔ\ÄÌ
!
ê
H4&c%/05(=
W

\ÄÌ
#
t{ɛ3H
$

%!Bc(%I$));
74%G#$%5
m\Ñ
m\Œê1›

P
.;><3
$UA%5)(;1
L
!^MM <.a%
!
.M N`M!M _`[!P M`M!P M`^!
P P`X nW!P N`O $ ($G#!O.!0!2(%2I(2#A&%!W P`O $O.!
0!>.=G%!L M`O $P.!5!UYN`^ .a!
Ys()’’ã
sYLnf
%!L W`O $P.!c%0!.;PW%!N N`[ $P.!5!
UY_ W` .a>.=G %&
PO
;><3 $ UA%5)(;1
L
! PMM
<.a%
!
.ON X` $;P%!WX O` $;W%!N_ P` $;O%!O_ W`
$;^%!LL N` $;L%!PN L` $;X%!OO O` $;[%!O_ N`
$;N%!^[ O` $;_%!O[ M` $;PM%!WO N` $;PP %!
PWW O` $;PW%!P^L P` $;PO%!^W M` $;P^%!OX P`
$;PL%![^ [` $;PX%!^N _` $;P[%!^P`^ $;PN%!
^[ P` $;P_%!OP M` $;WM%!OX W` $;WP%!OW N` $;
WW%!WN P` $;WO%!P[ M` $;W^%!PL L` $;WL%!P[`^
$;WX%!W[ W` $;W[%!PNM M` $;WN%!OO O` $;W_%!
W^ [` $;OM%!PM^ _` $?&G!;Pg%!LN M` $;Wg%![X P`
$;Og%![W X` $;^g%![N W` $;Lg%!XO M` $;Xg%&
Y
s()’’
;Wg
#ô[|ZsSnf !
.P[M W`
$>.=G!YT% WO [` $>.=G!.
O
%
_()i7
«
_(
1:[\ÄÌ
O;$W;$G(2$I5/;W;5(/KA;
#
6@;
*&4G/UA%$)/0A&% /KA(;PX

;#A5%/KA/&($);PW;();WN;/G
$G5
[()|Ì

\ÄÌ
$
t{3H
!
]:4W_-lXu
{
!
.-êM{
!
½01rŒ]—s

i
J(P
O
u{
çÛm\}ÝX{1›m!
½èlUs
-1:;<1
KR + › L k
SMPX_ < Q.(
Q

P
.;><3
$R
O
TR
O
!^MM <.a%
!
.[ P`L $W.!0!.;W!X%
PO
;
><3$R
O
TR
O
!PMM <.a%
!
.PWP _` $;P%!PPM P`
$;W!;X%!P^L _` $;O!;L%!PON [` $;L%!PX[ _`
$;[%
_()i7«
PM(
1:[()|Ì
!
Õ
ÕÔ\ÄÌ
$
êp¾L@
$*$&/A&$G5%
\ÄÌ
%
áM{3H
!
]:4W_i
J(P
O
u
{çÛm\}1›
!
½èlUs
-1:;<1
KR+›
Lk
SMP_[ Q

P
.;><3$R
O
TR! ^MM
<.a%
!
.X _`_ $W.!0!.;W!X%!^ W`P $W.!]!UY[ W`
.a!;T.
W
.
O
%! P W`N $ O.!2!UY[ W` .a!;T.
W
.
O
%
PO
;><3$R
O
TR!PMM <.a%
!
.PWP N` $;P%!
PPM M` $;W!;X%!P^X L` $;O!;L%!PO_ [` $;L%!
PXN X` $;[ %! XP [` $;T.
W
.
O
%! P^ X` $;T.
W
.
O
%
_()i7«
PM(
1:[()|Ì
!
ÕÕ
Ô\ÄÌ
%
êp¾L@|]
$(2#A&*$&$2(%
\ÄÌ
&
t{3H
-1:;<1
KR+›Lk
SMW_Pj
!WN_Q
&

(
WM
R
j^ [`u$)
M X`M!<(T.%!R$<(T.%
.
I$K
$
67
% WMP $_ M`^%!
WW^ $;W _`P %! WXL $;M [`X %! W_X $;P [`W % )I&
P
.;
><3$R
O
TR
O
!^MM <.a%
!
.^ L`X $P.!5!UY[ X`
.a!.;W%!O N`N $W.!I!.;O%!W L`W $P.! 55!UY
PX M`!N M` .a!.;^$%!W _`M $P.! 55!UYPX M`!L W`
.a!.;^c%! L N`[ $P.! 5!UYW`^ .a!.;X %! X M`P
$P.!5!UYW`^ .a!.;N%!X N`N $P.!5!UYP X` .a!
.;Wg%!X [`N $P.!5!UYN M` .a!.;Lg%!X [`^ $P.!
55!UYN M`!P X` .a!.;Xg%
PO
;><3$R
O
TR
O
!
PMM <.a%
!
.NW X` $;W%!XN O` $;O%!WN [` $;^%!
PL[ P`$;L%!_X P` $;X%!PL[ X` $;[%!_L`^ $;
N%!PLX _` $;_ZN$%!PMM X` $;PM Z^$%!POW P` $;
Pg%!PPL![ $;Wg%!P^L L`N $;Og%!P^L X`^ $;^g%!
PPL W` $;Lg%! PWM M` $;Xg%
_()i7«
PP(
1:[()|Ì
!
ÕÕÔ\ÄÌ
&
ê
$ j%;
-
§—
$ j%;G$2(G#)(
/M[[P/
{
OX
ï{
PO
•
WMPP
÷
[
²
!!!!!! ! ! ! ! ! !!!! ! ! ! !
S/&`OX! :004(!PO
94&A! WMPP
\ÄÌ

MÖ{3H
-1:;<1
KR+›Lk
SM^L_j
&
P
.;><3$R
O
TR
O
!^MM <.a%
!
.L P`L $P.!5!UYL W` .a!.;W%!L`^W $P.!52UY
L W`!^`^ .a!.;O%!W [`_ $P.!5!UY^ `^ .a!.;^$%!
W N`P $P.!5!UY^ `^ .a!.;^c%!X M`M $P.!5!UY
W M` .a!.;X%!X M`[ $P.!5!UYW M` .a!.;N%!X`^_
$W.!0!.;Wg!.;Xg%![ M`X $W.!0!.;Ww!.;Xw%&
PO
;
><3$R
O
TR
O
!PMM <.a%
!
.[N`^ $;W%![M W`
$;O%!WO`^ $;^%!PL[ P`$;L%!_X W` $;X%!PL[ N`
$;[%!_L`^ $;N%!PLX M` $;_ZN$%!__ M` $;PMZ
^$%!POM N` $;Pg%!PMX P` $;Wg!;Xg%!P^L N` $;
Og!;Lg%! POO W` $;^g%! PWP X` $*$&/A&! ;Pw%!
PM_ _` $;Ww!;Xw%!P^X`^ $;Ow!;Lw%!PXX P` $;
^w%!$?$&/A&!YT%
_()i7«
PW(
1:[
()|Ì
!
ÕÕÔ\ÄÌ
X
ê
$ Q%;
p¾L-§—p
¾L@]
$ Q%;*$&/G$2(G#) *$&$2((
%
ãÌT›

<@@
”
!
AÇh¨\ÄÌ
!
Ñ
#
vÉ( 
¡¢£¤T›¯#
!
§¨0•RYs’h\ÄÌ
#
A²¸´[
L
 ±¬ ¡¢£Y
$.@;N!7(&;
[^MW!7?;NWO!=L^_
Ñ
=W[NM%
r
=W[NM
¢£wè
.u[´µ›ÑÜT›
!
ª
:
LM
P [`W
!
I/&/B
QP

f\ÄÌ
!
A²¸´[
L
 ¢£YŒ,.u[¢£
¤T›
$:
LM
kPM
!
I/&/B
QP
%
$
žŸ
%!
*ö()Gr­þ]ö]‘øùÄÑþ]‘
Ç̃„²6‹%çrß%ç

$
‘’“
%
P (!
3/Ê
!
Ճ
`
r­è¤ÉÌ
<(`
øù
.
ö]K©
!P_N[.
PN_`
W (!
,jÁ
`
r­²öÉÌ6¨Fã¢0
9(`
É̃„
! WMM^!
W^$P%.P`
O (!?4)$0(V(%$1 8!/%5(&?=!J$%)0E/%2# >3` /)02242()20/6
?/!2$)$.&=/33.!/4.'(`9>$28%/5! P_NW!^L$L%.XLP`
^ (! 7#$%*$D$C8!?4U2$7/60$U/))0$)5 /2#(%)$24%$&U%/54G209(`:)5$) 9<(5 3(0!
P_[M!LN$X%.[W^`
L (! 1$K()$SC!1)*#$&<` 7/$G2D(6&$D/)/5$&G/)0224()206%/I
?/!2$)$.&=/313.)$$&($D(0% 9(`9:)02#(I$&G42$!P__N!
[M$L%.PXN`
X (!
¾Ç?
!
¾:.
!
¹1e
!
‡
`
§ê*QE¤èéÚ6ƒ„
9(`
r­rÇ£¤
!WMMX!OP$L%.O_[`
[ (! <$1 ?!.4 f!f4 1 1!(2$&FA2/2/KG2%2(%U()/5 0$U/))0
$GA&$2(5 E2# I/)/2(%U()G$G5 6%/I?/!2$)$.&=/3.3)/139(`
9>$28%/5!WMMN![P$P%.^P`
N (!:V(5$@!J4HE$%$1!=%$VC` A2/2/KG*&AG/05(06%/I+.=/M/0
:3./=#/*/, 9(`9>$28%/5!P__[!XM$W%.PMW`
_ (!
Å2C
!

!
3²Ó
`
&™²\]Ú6ƒ„
9(`
r­r
Ç£¤
!WMM[!OW$WM%.WPOL`
PM(!
)64
!
¾5
!
9љ
!
‡
`
™ŠK™,g[\]Ú6ƒ„
9(`
r­rÇ£¤
!WMMX!OP$WO%.P_LO`
PP(!1(2/3!>$V$I%$.!>$)H/J!(2$&`8%(U$%$2/) /6(UI(%0/62($
G$2(G#)0cA#($22%($2I()29(`7/0G7/2(G# 7/G#(I!P__[!
XP$_%.P^O^`
PW(!9(/) 1 f!7$(C.!1(/)*f.!(2$&`?%(() 2($G$2(G#)0$0$
7=-P $;1(G%(2$0(% )#c2/) 9(`7//%*<(5 #(IB(2!
WMMO!PO.O_ML`
2EA.0T/1TBCKD0DIACDKLGB.DEAGBBDKBL!*.5%-%&1/*#7&#-*2#7
/CHDEA0GTFDBDBP0T/TD0R0DF
<=1#4$)**$)*! BS.$))*! R:>??4$)*a#! f,1#0#$)
!
! .->+$/*4$)*
$>,*!/!3!$&4<0!$#/0 <$1/)0! 52/,$*$+)01$(&4<$1/)0.)/$,)$*0,1 ?$^/,- ;,/&, <$1/)0.5&.$-$! !0!$
Q$(F0=�!&#(&4A/&0)!/7$3=*!0,)$*0,1 H3,)!/&,*&4D0!3#0.<$1/)/,$*! A$/:/,- PMMMLM! 52/,0%
6NKDG/TD(! 1KG/IU/4)50E(%(0/&$2(5 6%/I2#(%//20/6?/!2$)$.&=/3.3)/13cAD$%/40G#%/I$2/*%$#G2(G#)]4(004G# $0
G/&4I) G#%/I$2/*%$U#A/) 0&G$*(&$)5 1(U#$5(KB.;WM! $)5 U%(U$%$2D(.8B! $)5 2#(%02%4G24%(0E(%((&4G5$2(5 $0H4&c%/05(
=
W
$!%! O;$W;$G(2$I5/;W;5(/KA;
#
;@;*&4G/UA%$)/0A&%/KA(;PX

;#A5%/KA/&($);PW;();WN;/G$G5 $#%! *$&/A&$G5 $$%! (2#A&*$&$2(
$%%! $ j%;G$2(G#) $&%! $ Q%;*$&/G$2(G#) *$&$2($% /) 2#(c$00/60U(G2%$0G/UG5$2$$)$&A00F/IU/4)50!; E(%(0/&$2(5
6%/I?/!2$)$.&=/3.3)/136/%2#(6%022I(F/IU/4)5 # 0#/E(5 0(&(G2D(GA2/KG$G2D2A$*$)022#(#4I$) G(&&)(0=W[NM E2# $)
:
LM
D$&4(/6PF[W
!
I/&/B
QP
F
ZAF VBGHK( !?/!2$)$.&=/3& ?/!2$)$.&=/3.3)/13& 2%2(%U()/5 0$U/))& 6&$D$)(& GA2/KG$G2D2A
HB0.!+\%#)QT[T..#+!!!$!
$
”•$Q
!
¥Z¦
%
/P[[P/
{
OX
ï{
PO
•
WMPP
÷
[
²
!!!!!! ! ! ! ! ! !!!! ! ! ! !
S/&`OX! :004(!PO
94&A! WMPP