免费文献传递   相关文献

Research on good usage practice for Chinese Materia Medica (I): chemical equivalence of different prepare procedures and optimal conditions for good clinical usage of rhubarb

中药调剂规范化研究(I):大黄不同调剂处理的化学同质性及条件优选



全 文 :$,ÛÜÝÞB‘’
!:#
ÌÎ}~ÛÜÔÕ
ŽB~‡€­ßàáâ

!
!zz
! *
!
{|]
*
!
:}

!
+~;
! *
!
L€
! *
!
3‚

!
e
€8
)$*
l< 8pECDG
!
rk
$$$)7%
*e
‚_plEž E<
!
‚_ ƒ„
&$*$(#
!!

de
#!
Qf
$
éÔB~‡€¸¼Ì΅‰,¦ÝÖ­ÛÜÔէǞ‹Õ,Ž¯°ÝÝ
*
gh
#
…‰,
¦
%
hiÁÜ
%
hiR:
%
hi™=
%
ìß
=
jßÔÕ5ΧÌÎ{|I;»\ž®Ž¯°
*
ij
#
ÌÎ}~,¦…‰À
=
£hR
k{|hi®Ÿ¶…
e7=#e&

,
À
=
£h}~R:Ÿ¶…
*e*=e(

,
À
=
£h}~™=Ÿ¶…
*e(=e(

,
À
=
£h
ìߐjߟ¶…
*e)=e%

*
ÞB~‡€]´
$
|°º}~ÛÜÔՎÆE=Žhi—×}~‡
*
d$
$
¹~ÔÕ5
Îߣhž½Ž{|„÷“®EŁÔÀhž½
*
ÀhiR
$$e( fe* -/
ŽÌ΅‰hi®
$
ŸþV*¡jhi®¹
¶}ÌÈç¹ò
,
ÌÎìßhiR{|hi®›ÀhR:1«´µÄ›¬­
,
jßhi
)$$#$ /N1
R{|hž®×Ôì
ß5Î
,
Àh@
*
™{|hž®þ…hi
#
™k®Ž
$g*
Õ£hiÌÎR
$
¨*Žhi®
$
Ÿ
$$$
íþV*¡hi®
¹¶}Ì
,
jß5Îhi®×ÓÔìß5Î
,
£h
)$ /N1
jhi®›}ÅÒ
,
£h@
*
™{|hž®þ…hi
#
™k®Ž
%$g*
¯‹°^
$
ÌÎÀhRjßhi
)$ /N1$
hi
*
™¸ô
,
£hRìßhi
)$ /N1
¸ô
$
hi
*
™¸ô
*
ik
#
}~ÛÜÔ
Õ5ΧÌÎ{|;»Žhi®EÅÒ¯°
,
óÍ;Ö$,ÛÜ9yÝÞ
!D..I HOBDMACB-@N-M$ ]KF*

lmn
#!
$,ÛÜ
,
9yÝÞ
,
B~‡€
,
ÌÎ

op-F
#!*$$*)$$%

qrsQ
#!

&
Ã̉,õ+

&(ÃÌqì
!*$$7 P`$7$*4$**

tbuv
#!
!
!:Ê
$
‘’x
$
´µÞŸÀ!ǞŽ$,efB‘
’
$LMS#!$$##7)))**$T4/BNS# A?BC/B-5)$*2*#e-./
!!
$,ÛÜÎ7¯‹€è&
$
Îì()
€F¥Õ¢@ôŽry
*
$,…‰$|,Ž´
÷
$
$,ÛÜÝÞw˜Çž¢m€E瀎Ÿ
j둢*
$
äŸÃµŽPZ¨Î
*
ëÕ
$
í@$
,…‰Û܅$©ÙFõÝގI5
$
N˜®
õf
%
Ì:Ûk}×-³óÈö
$
Յ‰,¦}×
L‹¯°jç
,
~R
$
Û܅$…‰hi5Î
%
Áܐ™=ŽâÍ¡àÝÞ÷H
,
}~Ì:Ý
֎…‰®b7}b
,
Ìñ:;×¥ø&p
q‘’=»Žiþ
*
ÞdÛÜ:;¢³$|,Žj
琢m
$
™ÛÜÔÕÆ~
$
ض…Ì
$
Eµ’Í~
æŽ$,‡®+
%
ùæŽ$|՘d0-Æ2è
EŽò—
$
@‘Åú
*
çAÝÌθ[
$
‘’}~…‰ÝÖ­h
i5ΧÌÎB~‡€
!
´µ,症;»“®
ŽÎs€

Ž¯°
$
¸$,ÛÜ9yÝÞB‘’h
¹p[ì°
*
¹¢Ac½aë½}~hi(Ár
·§ÌÎ{|;»\ž®Ž¯°
$
N¯T\qü‘
’ÀhŸ£h§ÌÎ{|hi܎¯°
-.
$
Ý­]R:§ªÌÎ$

†ºT{|Ž¯°-
-*.
$

5ΐßà§ÌÎ{|û‡;»“®Ž¯°
-).
-
*
ME¢ÛÜÔÕ5ü§ÌÎ{|;»hi®Î
s€¯°Ž‘’‹f»aë
*
!
Z[
YB@MCO3-_HN@5KFG<
þçK¹LÚU
!YB4
@MCO$ 9NSR.CI$ 93$ K83$æø»ŠŠ¦
ò
![BCNB1 3HO@CBSNBFL^ GLW$GW&4*
TVw
!
23
|TVw`
*
§¤½ÌÎÆ
%
ÌΙ
%
ÌÎQ
%
ÌÎƘ›
%
è
üÌÎÆ
%
õ`ÒQ‰ê$%,½ª—+½Wþ|
!
:<»…¸
$%74*$$$$ $%7#4*$$%#$$%%4
*$$*$#$ $%(4*$$#$$ $%774*$$($#$ $%*4
*$$#$($
˜£
!
»¼U­LÚU
$
^23(žñª—
()EFGHh¹
*
ds\Ü׸»¼U
*
Ì΅‰^×ÇQu
)$*
|_$,Ìh¹
$
¹
!:ʑ’xbþ¸ý&›—,ÌÎ
#$-74%:!
+,)(-UBNSe
Ž(Á#­# 
*
þV*^23PP
…8EFؑGH* r
*
(!

(W!
}~…‰ÝÖÌÎ,Z+}
+%(+
u
)#
‡u
*
w
*$
o
#
p
!!!!!! ! ! ! ! ! !!!! ! ! ! !
[.Se)#$ :OOHM!*
VH1M$ *$
i-®Ì΅‰
(
@*¡
$
»…+,¦¸
)e$ f&e$ -/!
4ƒÌþ…‰
$e f*e -/$$e( f
e* -/$($

/!
à*
$*$

/!
$*
$$

/!
¨
*
$M
7$
k)

/!
þV*
$$
í
$M
7$
k

/!
þ
V*
$$$
í
$
}
*
(W(!
Àhž½Ž+}
(W(W!
}~\]R:ÌÎÀhž½+}
!
#ȍ
‘’@wpqVèâi
(W
ìß
$e( fe* -/
…‰
#
@
$
v@9
)$ D$
~æ˜þ
$

$
®âÿÀ
$#
@ž½º™»…ó9hih
$ )$$ &$ #$
-&.
$ 7$$
*$ /N1$
hi

™
$
»…tó?ÁÜ
$
ZÑ(Á
$
˜ÃÍòŒ(õEÜ
-
õEÜ
j
(õÃ
!D=
˜,®
!D m$$g.$
(õ*©Ç}
*
(W(W(!
}~\]™=ÌÎÀhž½+}
!
~Þi
(W
ìß
$e( fe* -/
Ž…‰

@9
)$ D$
~æ˜
þ
$

$
®âÿÀ
$
ó9hi
#
™
$

)$ /N1$
»…tó?ÁÜ
$
ZÑ(Á
$
˜ÃòŒ(õEÜ
$
(õ*©Ç}
*
(W(W&!
ìßjßÌÎÀhž½+}
!
~Þi
(W
ì
ß
$e( fe* -/
Ž…‰
#
@
$
v@9
)$ D$
~æ˜þ
$
d$
)
@ž½»…
$
®âÿÀj
$
º™ó9h
i
$ )$$ #$ /N1$
»…y¸ìß
$)$$#$ /N1
ÌÎ
Àhž½
,
z
)
@ž½Í7I$
$
®âÿÀÖã
j0
$
»…ó9hi
$)$$ #$ /N1$
y¸jß
$
)$$ #$ /N1
ÌÎÀhž½
$
nêtó?ÁÜ
$


$
»…˜ÃòŒ(õEÜ
$
(õ*©Ç}
*
(W&!
£hž½Ž+}
ˆâÿÀ!¸
%$g

-.
$
ds~Àhž½
*
(Wa!
†{|„÷“®ýþ
(WaW!
§¤½ÁKŽ+}
!
~æ˜iÌÎÆ-

†
§¤½è®
$
ŠÔ~ήI$
$
0˜£Á×Í$J
lJ¦
$
KL
*
E=ÌÎÆ
%
ÌÎQ
%
ÌΙ
%
èüÌ
ÎÆ
%
ÌÎƘ›‡®Ë¦×¸
&$ /D+G
d
Ž¿‹§
¤½ÁKy¸Ž}K
*
ˆ6Ž}KZÎþ[$J
;“n;»
& /D+G
d
ŽÁKy¸§¤½ÁK
*
(WaW(!
¹\½ÁKŽ+}
!

#$
íÌÎ,Z*
Æ9
$e D$
~æ˜þ
*

* /G
˜£Òó9

?$
Ç*
$
˜£ÏpÆÃ
$
KL
$

*
~æ®i2
QK
/G$
\2˜£
$

(g
0QÁK
$ /G$
þ
ÔÕ
* /N1$
ÿOƒ˜#
$ /G$
Òó9
?$
Ç
*
$
Š»K#$
$
»iOƒ˜#v
$
QKÿOƒ
˜#$i
)
™
$

$ /G$
‹ÍOƒ˜#K
$

ó?ÁÜl(
$
f˜£ÍÁ×
$
ïgl
$ /G
®
I$
$
˜£lJ¦
$
KL
$
…
$e**

/

$
¿E
*
(WaW&!
LÚßà
!
ZAc5ü
-#.
WýÌÎ$

†
{|;»“®
* UTE<
(
LÚÜ
!*e //m$ //$
e%

/$
9`¹˜£
4$eg
yQÀÁK
!#&r)#$
9
á
$e# /G+/N1
d
$
Sž®


G$
Wýb«
*& 1/$
Üh
) i*
ÝÕY%=ZÌÎÆ÷òŒè}ÓÔ
* $$$*
¸½q˜¶5üµ’€
$
çA§¶5üŽ~æ
¦
%
Àþ€Ã%€Sd°º
$
ŸAcVèÎs
*
&!

&W!
…‰,¦§ÌÎ{|;»\ž®Ž¯°
§}~,¦…‰hiV菐c³
$
Ì΅‰,
¦Þ
) f& -/!
4ƒÌþ…‰

 ¡t:=þV*R
$
Àhi\žŽ{|k®Äìtj›ÿt—¢›Ž
bB¬­
$
d$
$e( fe* -/
Ì:Ž…‰þV*¡
Ž…‰hi®
!
g
,
Õ
%$g
£hiR
$
Ì΅
‰,¦bB§{|\ž®Ž¯°ÝݟÀhi}~
$
éçÞÄ,¦:\ž®ÌŽbB¬­
$
d$¨*

$$$
íþV*Žhi®
!
g
**
g
!
ÀhiÌÎ}~,¦…‰{|;»\ž®
g
*!%$g
£hiÌÎ}~,¦…‰{|;»\ž®
&W(!
hiR:§Ì΅‰{|;»\ž®Ž¯°
Ì΅‰>ÀhiR
$
Ù
#$ /N1
8{|\ž
®›hiR:1« ¡›
$
M
7$ /N1
RJÕߢ
$
hiR:1«=
*$ /N1$
\ž®¢›
$
M¹§Ô
#$
/N1
›Í}ÅÒ
*
£hiR
$
Ù
7$ /N1
R\ž®‡
+((+
u
)#
‡u
*
w
*$
o
#
p
!!!!!! ! ! ! ! ! !!!! ! ! ! !
[.Se)#$ :OOHM!*
VH1M$ *$
ŸL
$
M¹§Ô
)$ /N1
›Í}ÅÒ
!
g
)*
g
)!
hiR:§Ì΅‰{|;»\ž®¯°
&W&!
hi™=§Ì΅‰{|;»\ž®Ž¯°
}~hi™=
!

)$ /N1
ŽVè
$
u

™hiŽ{|®ÅҁÔdjhi
$
£hž½-¸

!
g
&*
g
&!
hi™=§Ì΅‰{|;»\ž®¯°
&Wa!
ìß
=
jߧÌ΅‰{|;»\ž®Ž¯°
ìß
%
jßÔՎž½
$
VèÅ¥Àhi
R
$
jßhi
)$$#$ /N1
R{|\ž®Ôìß5
Î
$
Õjßhi
/N1
\ž®JÕÓÔìß5Î
*
£hiR
$
jß5Îhi®×ÓÔìß5Î
$
d$ì
ßhi
)$ /N1
Ž{|\ž®Ÿ
!
g
*
g
!
ìß
=
jߧÌ΅‰{|;»\ž®¯°
&W$!
hiÁܧÌ΅‰{|;»\ž®Ž¯°
Þg
f
µ»
$
¹~ÔÕ5Îß
$%$g
4£§
ÌÎ{|Žhi®éçÞ7ÔÀhi
*
a!
¼Y
fP€Îs€$,ÛÜ9yÛR‡=Žé
çµó
*
M^Ôí@§$,ÛÜÝÞ¢ÿ—
$
Ù,
Ìk,ÛÜPZfP€Îs€¶Ž:;Üe
œž
$
ú@é¡$,ŽÎs€:;
$
}~ÝÖ-1
,ZŽÎs€:;
$
Ý­…‰,¦×L€Îs€
$
}~\žÔÕ5ÎÎs€âͺ»-
-%.
*
[N
$
Ì
Î]êÔ
)
“顽†
$
ú@
)
†´µÝ֐“-
1
$
‘’†E}~½†
%
ÝÖ-1ÌΎ´µ,ç;
»“®ª—çK¶·Ì¾l‡=
) f

-(.
$
Õ
^Ôí@$,k,ÛÜPZ¥ø&ÝÞ
$
~ÎG
Ô5Ù}~,Ì|&$,‡®µ’¹¶FÌ
$
”̯
°jçc*
}~½†
%
ÝÖ-1ÌΎB“®
ª—çKÎs€½E:푒
$
çA´µ7§}
~…‰,¦
%
\]ÔÕ5ΧÌÎ{|;»hi®Ž
Îs€Sd§‘’
$
E´µ¯°ŽÆÍáâŸY
\h5Î
*
‘’†E
$
ÌÎ}~,¦…‰À
=
£hRk{|
hi®Ÿ¶…
e7=#e&

,
À
=
£h}~R:Ÿ
¶…
*e*=e(

,
À
=
£h}~™=Ÿ¶…
*e(=
e(

,
À
=
£hìߐjߟ¶…
*e)=e%

*
ÞB~‡€]´
$
|°º}~ÛÜÔÕßàE=
Žhi—×}~‡
$
N}ÝÿòÝÞÛ믰
ǞjçŽÀþ€µ’€
*
«wÝ]
$
¤Y$
|&‘7$,&‘
$
7¢ÿ‘’nêˆGŽ
:;
$
§$|Ÿ$,¨:Ž
&
„åV‹1
///

ǞŽ$,efB:;N$,ÛÜ9yÝÞÎ6¢
ÿ}h
$
‘’}
*
ÞçA‘’Vè]´
$
$,ÛÜ
9y}~§Çžj篰Ì
$
Ž6;°ì¤
]9F
;Ö$,ÛÜ9y݁
!D..I HOBDMACB-@N-M$
]KF
-7.
$
ÝÞ$,ÛÜ9y
$
gÚ$,Ǟ¢m€
E瀎ŸjÎë¢*
*
§}~ÛÜ9yŽhiçè
$
µÝáâÌΟ
YÛÜ5Î
*
N¹~ÔÕ5Îߣhž½Ž{|„
÷“®EŁÔÀhž½
$
̟{|I;»§c”€
Ó
$
ÙEwÁÜ$Á׀¹§ÌE¢
*
Mhi
ÁÜÌ#»pf̵âÍ
$
N´µÔ³ß
$
µâÀ
¸Ó˦Ž4£¸hiÁÜ
$
hžV‹™{|
,
™
Ýŵ’hižnI{|;»¸íŽ
$
µấË
¦4£¸hiÁÜ
*
ÀhiR
$$e( fe* -/!
ΔÌ
:

ŽÌ΅‰hi®
$
ŸþV*¡jhi®¹
+7(+
u
)#
‡u
*
w
*$
o
#
p
!!!!!! ! ! ! ! ! !!!! ! ! ! !
[.Se)#$ :OOHM!*
VH1M$ *$
¶}ÌÈç¹ò
$
d®;̵4ƒÌþ…‰Ž
%$g
¿µ‡=¹~Ž\ž®
$
~R:¹,…‰7(E
×΀ڎá­
$
EÔw˜ÇžÛ܎fP€
*
›
œÀhi
!
ìß

R:1«
$
{|„÷hi®´µÄ›
¬­
$
À#$ /N1
hi®
,
Õjßhi
)$$#$
/N1
R{|\ž®×Ôìß5Î
*
Àh@
*
™{
|hž®þ…hi
#
™k®Ž
$g$
ÿ›hi™=
hi®›°±
*
¯‹°^hiçܐR:óÎ
$
Ì
ÎÀhRjßhi
)$ /N1$
hi
*
™¸ô
*
Õ£hi
ÌÎR
$
¨*Žhi®
$
Ÿ
$$$
íþV*¡hi
®¹¶}Ì
,
jß5Îhi®×ÓÔìß5Î
$
d$
ìßhi
)$ /N1
Ž{|\ž®Ÿ
,
£h
)$ /N1
j
›}ÅÒ
$7$ /N1
jJÕߢ
,
£h@
*
™{|h
ž®þ…hi
#
™k®Ž
%$g$
ÿ›hi™=hi
®›°±
,
¯‹°^
$
ÌΣhRìßhi
)$ /N1
¸ô
$
hi
*
™¸ô
*
Þd_§ÎYabŽ»¼
$
pfè$µ#»Œ(Ìó‹ÕâÍÛÜ9y
*

waxy
#
-.!
Î8
$
y·H
$
G.n
$
-
,
¯T\qü‘’ÀhŸ£h§Ì
Î{|hi܎¯°
-V.,
$;,
$ *$$)$ *!&# *%),
-*.!
ø\>
$

$
¸)Ü
,
\]R:§ªÌÎ$+†ºT{|
Ž¯°
-V.,
!$|,Ìa
$ *$$($ )*!# #%$,
-).!

$
p<
$
Ą
$
-
,
(Á5ΐßà§ÌÎÀhK{|
û‡;»“®Ž¯°
-V.,
$%$,-.
$ *$$($ ))!(# (7),
-&.!
“‚H
$
s;ª
$
è¨<
,
hi5ü§ÌÎ$k{|“®Ž
¯°
-V.,
³Sè,
$ 77)$ $!# )),
-.!
67j
$
!:Ê
$
^\]
$
-
,
ÌÎ\]…${|I;»`
abBÝݑ’
-V.,
×ÇQ,a
$ *$$#$ **!&# *(,
-#.!
1*+
$

$
!:Ê
$
-
,
éÔB»¼ŽÌÎ,ZT½
ÝÖó»Ž&‹Õ€‘’
-V.,
$%$,-.
$ *$$$ )
!&# &%$,
-%.!
,U-
$
6@.
$
ðÂ
,
õ2Eç;»hißàŽ‘’
-V.,
s5,
$ *$$$ !&# )#,
-(.!
1*+
$
Ą
$
&+•
$
-
,
³ßI$,‡®Žª—+5ü
­éç:;¸¼
-V.,
,a
$ *$$7$ &&!# $$,
-7.!
!:Ê
$
1*+
$
S^€
$
-
,
À!ǞŽ$,efB‘’
-V.,
kU&()
///
$|,³SB
$ *$$$ *!&# #%,
8?I?-ERC@AS@@FGI-S?KE-RB.R?J@E0C.A?I?<-B?E.- RC?,.R-/?VG.P-/?AR?@JF.JJ?E?ABKE?K-E?KE@R?FGE?I-AF@KB.,-/
R@AF.B.@AIJ@ES@@FR/.A.R-/GI-S?@JECGL-EL
Y3;]VNB\.

$ G:KaMNRMN
$ *
$ P:3PN1?HB
*
$ V:;
$ E`QK$ *
$ E`3;]PHMCH
$ *
$ P:3QPNB.?M

!
!eA$,) 3(6)25H,*6676-%:A$,-*-3)6-2) 3-&+)$ )$* 3(6)25G%*?6)($ R-C,@ $$$)7$ A$,),
*eA%(-@-%:.$)24)+5$ G7,), =,>-2*65%:E2)&6%,)(A$,-*-3-&+,-$ A$),@*$) &$*$($ A$,)
!!-4LIBE-RB.!6L]?RB.P?# L.AC.\MN1@.@?MN1RSHM1-MO.RINRMCM1@DCB1HSMONXMOB1I @.ACMABCMAC.-MIHCMO.1 CB@N.1BS-SN1N-BSHO4
BDM.RC?H\BC\ \BOMI .1 -?M/N-BSM_HNhBSM1-MeACM4M6@CB-@.CAC.4M6@CB-@.RC?H\BC\ .1 @?MM6@CB-@B/.H1@O.R@?MB1@?CB_HN1.1MO!3cO +MCM-./ABCMIe8?IG/B#L?MINRMCM1@ACMABCM
AC.-MIHCMON1hMO@NDB@MI N1 @?MABAMCCMhMBSMI OND1NRN-B1@N1RSHM1-M.1 @?MM6@CB-@B/.H1@O.R@?M3cOB1I @?.OMM6@CB-@O+MCM1.@-?M/N4
-BSM_HNhBSM1@eT@?B1.SM6@CB-@MI /.CM3cO@?B1 +B@MCINI$ +?M1 .@?MC-.1IN@N.1O+MCMOB/MeY?M1 M6@CB-@MI +N@? +B@MC$ @?MC?H\BC.RANM-MONXM$e(4e* -/-.HSI M6@CB-@CMSB@NhMS5?ND? B/.H1@.R3cO1MBCS5M_HBS@.OHAMCRN1MDCN1IMI A.+IMCO$ B1I @?MR.C/MC+BO
-?MBAeL?M+B@MCM6@CB-@N.1 .R3cOO?.+MI B1 N1-CMBON1D@CM1I +N@? @?MM6@CB-@N.1 @N/MM6@M1IMIe31I AC.4M6@CB-@/B11MC+N@? +B@MC
-.HSI M6@CB-@/.CM3cO@?B1 ACM4M6@CB-@/B11MC+N@? BM6@CB-@N.1 @N/M.R)$$ #$ /N1eL?M+B@MCM6@CB-@N.1 .R3cOCMAMB@MI @+.@N/MO
M6-MMIMI ?BSR.R@?MB/.H1@.R@.@BS5ON6@N/MOeY?M1 M6@CB-@MI +N@? M@?B1.S$ @?MC?H\BC\ .RRN1MA.+IMCO-.HSI M6@CB-@CMSB@NhMS5?ND?
B/.H1@.R3cO1MBCS5M_HBS@.OHAMCRN1MDCN1IMI A.+IMCOe31I ACM4M6@CB-@/B11MC+N@? M@?B1.S-.HSI M6@CB-@/.CM3cO@?B1 AC.4M6@CB-@
/B11MCeL?MM@?B1.SM6@CB-@N.1 .R3cON1-CMBOMI N1 )$ /N1 B1I @?M1 N1-CMBOMI OS.+MCeL?MM@?B1.SM6@CB-@N.1 .R3cOCMAMB@MI @+.
@N/MOM6-MMIMI %$g .R@?MB/.H1@.R@.@BS5ON6@N/MOe8.$ @?M.A@N/BS-.1IN@N.1OR.C+B@MCM6@CB-@N.1 C?H\BC\ +MCMAC.4M6@CB-@$ @+.
@N/MOCMAMB@MI B1I )$ /N1 AMC@N/M, B1I @?M.A@N/BS-.1IN@N.1OR.CM@?B1.SM6@CB-@+MCMACM4M6@CB-@$ @+.@N/MOCMAMB@MI B1I )$ /N1 AMC
@N/Me0@AR/GI.@A# L?MINRMCM1@ACMABCMAC.-MIHCMOO?.+MI OND1NRN-B1@N1RSHM1-M.1 @?MM6@CB-@N.1 .RC?H\BC\ 3cOeL?MCMNODCMB@1MMI
@.MO@B\SNO? BD..I HOBDMACB-@N-M!]KF R.C-Y?D U@EFI.!-SN1N-BSHOBDM.R
z{-0
!
ƒ„…
#
+$7+
u
)#
‡u
*
w
*$
o
#
p
!!!!!! ! ! ! ! ! !!!! ! ! ! !
[.Se)#$ :OOHM!*
VH1M$ *$