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作 者 ：奚胜艳,王彦晖,赵育芳,卢大为,李鹏程,张前

期 刊 ：中国中药杂志 2010年 35卷 10期 页码：1352.

关键词：中药复方；肿瘤血管生成；问题与对策；

Keywords:formulae of traditional Chinese medicine(FTCM), tumor angiogenesis, problem and countermeasure,

摘 要 ：恶性肿瘤是严重威胁健康的常见疾病。中药作为我国传统药物的主要组成部分,几千年来在肿瘤防治中发挥着重要作用。Folkman肿瘤生长依赖于新生血管形成的理论已经被证实多年,治疗肿瘤,抑制其血管生成是一种重要途径。我国在血管生成方面的中药复方研究起步较晚,虽有不少报道,但亦存在不少的问题。文章概括了近几年来中药复方抗肿瘤血管生成的相关研究,并在此基础上,对抗肿瘤血管中药复方的问题、对策、发展和方向作出了较为深入的分析和述评。

Abstract:Malignant tumor is the common disease that threaten severely to people‘s health. Formulae of traditional Chinese medicine(FTCM), as the major component of traditional drugs, has played more important role on the prevention and cure to tumor. The Folkman‘s theory that tumorous growth depends on tumor neovascularization has been confirmed so many years, so to inhibit the tumor angiogenesis, is an important path to treat tumor. The research of FTCM to antagonizing tumor angiogenesis in our country has been started more lately. Since it has been reported some FTCMs can inhibit angiogenesis, and it also exists many problems. The aticle summarized the correlated research of FTCM to antagonize tumor angiogenesis for the past several years, and according this, analyzed, stated and commented to the problems, countermeasures, development and direction of FTCM to antagonize tumor angiogenesis.

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