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Advance on targets and drugs for anti-HIV

抗HIV药物及其靶点的研究进展


随着AIDS在全球范围内的迅速蔓延,寻找有效的抗HIV药物成为研究的重点任务。作者主要综述了近10年来抗HIV药物作用靶点的研究进展,特别是以侵入融合过程 、逆转录酶、蛋白酶及整合酶这几个位点,以及在这几个靶点上的传统中草药中抗HIV的有效成分,和已经用于临床及正在研发的一些抗HIV药物。

As the spreading of AIDS over the world, to research effective anti-HIV drugs is required. The review contains the process of discovering targets for anti-HIV especially entry/infuse, reverse transcriptase, protease and integrase, and describes the effective component of traditional Chinese drugs for these targets and the anti-HIV drugs being researched or used in clinic.