Abstract:Objective: To evaluate the effectiveness of Shenwu gelatin capsule (compound Chinese ginseng and fleeceflower root etc) in the treatment on senile mild cognitive impairment. Method: 166 patients meeting criteria for mild cognitive impairment were selected from patients in Dongzhimen Hospital and were randomly assigned into a treatment group (n=83 cases), given 5 capsules of Shenwu gelatin capsule, and a positive control group (n=83 cases), given 2 capsules of aniracetam with 3 placebo capsules. All subjects took this medication 3 times a day for 3 months. double-blind and double-moulding control were used in this study. At a baseline and end (three months later), all subjects were assessed using a battery consisting of MMSE and clinical memory scale (CMS). Result: Both Shenwu gelatin capsule and aniracetam can remarkably increase the score of memory quotient (MQ), P<0.01. They have the similarly effectiveness, there are no statistical difference between the two groups in effectiveness of increasing memory scores. Conclusion: Shenwu gelatin capsule has certain effects on mild cognitive impairment.