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期 刊 ：中国中药杂志 1998年 23卷 09期 页码：558.

关键词：桂枝茯苓丸；脑缺血；钙；

Keywords:Gunzhi Fuling Pills, cerebral ischemia, Ca2+,

摘 要 ：目的:研究桂枝茯苓丸加减方在脑缺血及再灌注模型中血清及脑组织中谷氨酸(Glu)、天冬氨酸(Asp)、甘氨酸(Gly)、γ 氨基丁酸(GABA)的变化。同时测定用药前后脑组织中Ca2+水平变化及脑水肿的程度。方法:氨基酸自动分析仪测定Glu,Asp,Gly,GABA。原子吸收分光光度法测定脑组织中的钙。结果:中药治疗组的氨基酸水平及钙含量与对照组有明显差异。结论:桂枝茯苓丸加减方对缺血性脑损伤有缓解作用。

Abstract:Objective:To Probe the action of the Chinese tranditional medicine Guizhi Fuling Pills on rats with cerebral ischemia and reirrigation.Method:The changes of Glu,Asp,Gly and GABA in serum and cerebral tissues were determined,and the degrees of Ca²⁺and the cerebral ebema were analyzed.Result:The contents of Glu,Asp,Gly,GABA and Ca²⁺in the pills treated group are different from those in the control.Conclusion:Guizhi Fuling Pills help alleviate ischemia induced cerebral injuries.

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