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期 刊 ：中国中药杂志 1994年 19卷 10期 页码：617.

关键词：西洋参茎叶皂甙；西洋参单体皂甙；豚鼠乳头肌；大鼠血流动力学；电刺激；

Keywords:PQS, monomer ginsenoside, papillary muscle of guinea pig, hemodynamic indication of rat, electricalstimulation,

摘 要 ：西洋参茎叶皂甙(0.03～3mg/ml)可抑制豚鼠乳头肌缩力,对高钾去极化标本,西洋参茎叶皂甙(0.03～0.3mg/ml)可使缩力增加。西洋参单体皂甙-Re10mg/kg,-Rb₃30mg/kg可抑制大鼠血流动力学LVSP,土dp/dtmax等指标,单体P-F₁₁10mg/kg与上述作用相反。证明西洋参茎叶皂甙中存在作用相反的成分。

Abstract:Experiments have shown that PQS(0.03～3mg /ml)can inhibit the contractility of papillary muscle of guineapigs,and on depolarized sample of papillary,muscle with high potassium,PQS(0.03～0.3mg/ml)can increase this con-tractility,Monomer saponin-Re(10mg/kg),-Rb₃(30mg/kg)can inhibit the hemodynamic indication of rats,but pseu-dogisenoside-F₁₁(10mg/kg)acts the other way round.These results prove that PQS contains two components ofopposite actions。

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