Abstract:Panax guinquefolium saponin (PQS) increases the contractibility of papillary muscle of guinea pigs during electri-cal arimulation with frequency of 1/8~1/64Hz (P<0.05). In Krebs-Henseleit solution purged with gas containing95 %N2 and 5% CO2 regardless of containing gluare or not, PQS (0.3mg/kg) has the effect of anti-hypoxia and anti-glucase deficiency (P<0. 05 ,P<0. 01) in the electrical stimulation with frequency of 1/8~1/64Hz.