Abstract:Six compounds were isolated from Veronicastrurn sibiricum and identified as D-mannitol, β-sitosterol, daucosterine, 3-0-acetyloleanolic acid, 3 4-dimethoxy cinnamic acid and isoferulic acid. Pharmacological experiment has shown that isoferulic acid is anti-inflammatory and amalgesic; 3-0-acetyloleanolic acid is anti-inflammatory; mannitol is analgesic., 3. 4-dimethoxy is also anti-inflammatory and analgesic.