---

期 刊 ：中国中药杂志 1994年 19卷 03期 页码：174.

关键词：火绒草；Arthus反应；溶酶体；白细胞移行；

Keywords:Leontopodium leontopodiotdes, RPA, lysosome, migration of leukocytes,

摘 要 ：火绒草提取物(ip50～100mg/kg)对动物逆转性Arthus反应,抗鼠血清兔血清引起的足肿胀、溶酶体所致的出血斑、毛细血管返透性以及羧甲基纤维索引起的白细胞移行均有明显的抑制作用。此作用并不依赖于肾上腺和溶酶体膜的完整存在。

Abstract:The extract from Leontopodtum leontopodioides 50～ 100mg/kg ip has been proved able to suppress theswelling of normal or adrenalectomised rat hind paws induced by RPA,and strongly inhibit the cutaneous hemor-rhage of animals induced by RPA , lysosome or lysosome of broken membrane. It has also been shown that the ex-tract 100 mg/kg ip can markedly inhibit the migration of leukocytes. These suggest that the anti-inflammatoryproperties of the extract are not dependent on the pituitary-adrenal system or membrane of lysosome.

---