Abstract:This paper reviewed the newest research advances in insect pestsinduced plant defense, including insect pests-induced system wounding signals of plants, elicitors of insects, indirect defense, direct defense, and negative defense. In the interactions between plants and insect pests, plants can use the induced defensive substances to counteract insect pests, while the latter can use their specific elicitors to beat plant defense. This paper also compared the four metabolic pathways involved in indirect defense, i.e., lipoxygenase pathway, isoprenoid pathway, shikimate pathway, and extrfloral nectar, discussed the release mechanisms of induced volatile organic compounds in plants, and illustrated the conception of direct defense, defensive substances, and their action mechanisms. Finally, the research advances in the mechanisms of inset pests-induced negative defense of plants were reviewed, with the focus on the molecular mechanisms of insect pests-induced defense of forests.