Five compounds (1-5) were isolated from the rhizome of Beesia calthaefolia (Maxim.) Ulbr. Based on chemical and spectral evidence, their structures were determined as beesic acid (9-phenyl-2E, 4E, 6E, 8E-nontetraenoic acid, 1), vanillic acid (2), oleanolic acid-3-O-α-L-arabinopyranosyl-28-O-α-L -rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (3), hederasaponin B (oleanolicacid-3-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, 4) and beesioside Q (oleanolic acid-3-O-β-D -glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, 5), respectively. Compound 1 was isolated from natural sources for the first time and compound 5 was a new compound.
中国特有药用植物铁破锣中的新皂甙类成分
鞠建华1* 刘东1 林耕1 许旭东1 杨峻山1* 涂光忠2 马立斌2
（1. 中国协和医科大学中国医学科学院药用植物研究所，北京100094；2. 北京微量化学研究所，北京100060）
摘要：从铁破锣(Beesia calthaefolia (Maxim.) Ulbr.)根茎中分离得到5个化合物(1～5),经化学和波谱学方法鉴定,其中2个为有机酸--铁破锣酸(beesic acid, 9-phenyl_2E, 4E, 6E, 8E-nontetraenoic acid, 1)和香草酸(2);3个为齐墩果酸型三萜皂甙:oleanolic acid-3-O-α-L-arabinopyranosyl-28-O -α-_L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6) -β-D-glucopy ranosyl ester (3),hederasaponin B (oleanolic acid-3-O-α-L-rh a mnopyranosyl-(1→2)-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→ 4-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, 4) 和铁破锣皂甙Q (beesioside Q, oleanolic acid-3-O-β-D-glucopyranosyl_(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-28-O-α-L-rhamnopy ranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, 5).化合物1系首次从自然界中分离得到,化合物5为新化合物.
关键词： 毛茛科；铁破锣；齐墩果酸型三萜皂甙；铁破锣酸；铁破锣皂甙Q
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