Abstract:The epithelial-mesenchymal transition (EMT) is a highly conserved cellular process in which epithelial cells are converted into mesenchymal cells in specific conditions and this process is regulated by various signal molecules. Recent researches indicate that Trps1， a GATA-like transcription factor， plays a key role in maintaining epithelial phenotype and inhibiting EMT through regulating expression of multiple EMT-related genes， such as FOXA1， ZEB2， Pax2， Wt1 and Arkadia. In addition， Trps1 is also regulated by miRNAs in the process of EMT. This paper reviews the research progress about relationship between Trsp1 and EMT.