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作 者 ：崔 娜1,2,于志海1,韩明利1，董雪飞1,曲 波1,李天来2

期 刊 ：西北植物学报 2012年 4期 页码：843~851

关键词：14-3-3蛋白；发现；功能；基因鉴定；结构；

Keywords:14-3-3 protein, discovery, function, gene identification, structure,

摘 要 ：14-3-3蛋白是真核生物中许多信号传导级联反应的主要调节分子，易于与具有磷酸化的丝氨酸和苏氨酸残基的靶蛋白互作进而调节碳氮代谢、三羧酸循环、莽草酸合成等多种生理过程中的多种酶活性。该文根据近年来国内外对14-3-3蛋白的研究进展，对植物中14-3-3蛋白的发现、基因鉴定、结构和功能以及14-3-3蛋白与其靶蛋白的互作机制进行综述， 并对14-3-3蛋白的研究提出了进一步的展望。

Abstract:14-3-3 proteins are considered master regulators of many signal transduction cascades in eukaryotes.They can interact with target proteins containing phosphoserine or phosphothreonine to regulate the activities of various enzymes which relate to carbon and nitrogen metabolism,tricarboxylic acid (TCA) cycle,the shikimate pathway and so on.Based on the recent research status on protein discovery,gene identification,structure and function of 14-3-3 proteins in plant are summarized in this paper.Meanwhile,the mechanism of 14-3-3 proteins to interact with the target is described.Furthermore,we bring forward the prospect about the further study on plant 14-3-3 proteins.

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