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期 刊 ：中国中药杂志 2007年 32卷 12期 页码：1164.

关键词：逍遥丸；大孔吸附树脂；精制方法；

Keywords:Xiaoyao Pill, macroporous adsorption resin, separation and refine,

摘 要 ：目的：通过对12种大孔吸附树脂筛选,寻找适用于分离精制逍遥丸的树脂种类及方法。方法：以芍药苷、柴胡皂苷A、阿魏酸、甘草酸的静态、动态吸附量和脱附率为指标大范围筛选树脂,通过单因素试验确定分离精制逍遥丸的优选操作条件。结果：D-101-1树脂具有较好的吸附性能和解吸效果。吸附完全后,先以水洗脱,除去杂质,再收集50%及70％乙醇洗脱液,药材与树脂(干重)的比例为5∶1。结论：D-101-1树脂综合性能良好,适用于逍遥丸的分离精制。

Abstract:Objective: To search for the method used in refining Xiaoyao Pill by macroporous adsorption resin, 12 types of macroporous adsorption resin were optimized. Method: Static and dynamic adsorption test and de-adsorption test were carried out to screen the best macroporous resin. The single factor test was applied to optimize the manipulation parameters of macroporous resin. Result: The macroporous resin D-101-1 possessed the strongest adsorption ability, in addition to an easy de-adsorption property. Conclusion: The D-101-1 type macroporous adsorption resin shows better comprehensive adsorption property. It is available for the refine Xiaoyao Pill.

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