Abstract:Objective: to establish the optimum preparation procedure for Tongjingshu babu sticking plaster. Method: Orthogonal design was used to observe the adhesion power, cohesion by the multi-electronic experimental equipment. Result: The best formulation is composed of ointment, polypropylene acid, glycerin, bond and its proportion is 0.2:4:8:1.2, the final plaster contains 35 % water with idea stability to the skin. Conclusion: The formulation of Tongjing-shu babu sticking plaster is resonable and its preparation is simple and rapid.