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期 刊 ：中国中药杂志 2003年 28卷 07期 页码：606.

关键词：中药；川芎；色谱指纹图谱；中药质量控制；

Keywords:traditional Chinese medicine (TCM), Ligusticum chuangxiong, chromatographic fingerprint, quality control of TCM,

摘 要 ：目的:研究用于鉴别川芎产地的色谱指纹图谱分析技术。方法:用HPLC获得川芎药材的色谱图,从中提取15个色谱峰,再用主成分分析、聚类分析、相似度计算以及Fisher因子分析等方法进行考察。结果:不同产地川芎的色谱指纹图谱存在明显的差异,所提取的15个色谱峰可用作指纹特征。结论:色谱指纹图谱分析技术可用于川芎药材的产地鉴别。

Abstract:Objective: To establish the chromatographic fingerprinting for identifying the habitat of Ligusticum chuangx-iong. Method: HPLC system was applied to obtain the chromatograms of L. chuangxiong samples from different areas, and 15 peaks were measured from the chromatograms. Then some computer-based methods including principle component analysis, clustering analysis, similarity calculation and fisher factor analysis were applied for data analysis. Result: There was obvious difference among chromatographic fingerprints of L. chuangxiong samples from different areas. The 15 measured peaks could be used as the fingerprint features. Conclusion: Chromatographic fingerprinting can be used for identifying the habitat of L. chuangxiong.

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