Abstract:Objective:To observe the influence of alum on the intestinal microecological balance in normal microorganisms.Method:The mice were administered orally with alum of a small dosage(0.25/kg)and a large dosage(1g/kg)for halfa month,two months and three months,and amicroflora analysis of the micewasxarried out at intervals of the abovementioned adminostrations.Result:The intestinal flora in the animals administered with alum was imbalanced.The counts of bifidobacteria and lactobacilli closely realated to human physiological activities were decreased.The counts of pathogenic E.Coli significantly increased;and the longer the animals were treated with alum,the stronger the microecological balance was influenced.Conclusion:Alum could induce imbalance of the normal intestinal flora in mice.