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期 刊 ：中国中药杂志 1992年 17卷 04期 页码：233.

关键词：肝脏；丹参；脂质过氧化作用；

Keywords:liver, Radix Salviae Miltiorrhizae, lipid peroxidation,

摘 要 ：实验结果表明,丹参能明显抑制正常及损伤肝细胞脂质过氧化反应,诱导细胞色素P450的合成,防止损伤肝细胞蛋白质、DNA、RNA、尿素及铜兰蛋白的降低,减轻肝毒物对体外培养肝细胞超微结构的损伤。

Abstract:The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hcpatocytes of rats, induce liver microsomal cytochrome P₄₅₀ in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl₄. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver iniury.

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