Abstract:This article adopts macro-reticular resins to separate and get rid of water solubl impurities such as carbohydrate in Panax quinquefolium so as to dete mine its total saponin content by spectrophotometrv. This method also yields good results in determining the total saponins in P. ginseng ora solution. For the control or appraisement of the quality of preparations containing P. quinquefoliurn or P. ginseng oral solutions this method has practical value.