---

期 刊 ：中国中药杂志 1989年 14卷 02期 页码：46.

关键词：香菇菌多糖；廓清指数；迟发过敏反应；淋巴细胞增殖；

Keywords:PHL, phagocytic index, delayed anaphylaxis reaction, lymphocyte proliferation,

摘 要 ：香菇菌多糖能使氢化可的松诱发小鼠腹腔巨噬细胞功能低下和外周血T淋巴细胞百分率减少,醋酸氢化泼尼松诱发小鼠网状内皮系统吞噬功能降低恢复正常,并能恢复环磷酰胺抑制的小鼠迟发过敏反应,促进ConA、PHA诱导淋巴细胞增殖作用。

Abstract:PHL possesses significant antagonist action for immunodepression in mice induced by different immunodepressors. It can reverse the hypomacrophage function and the reduction in percentage of T-lymphoid cell induced by hydrocortisone(50 or 80mg/kg, sc), reverse the reduction of phagocytosis of reticuloendothelial system (RES) induced by hydroprednisone acetate(20 and 40mg/kg, ip), restore the cyclophosphamide-suppressed delayed anaphylaxis reaction in mice (40 and 80mg/kg, ip). In vitro PHL at a dose of 1 and 10μg/ml accelerated lymphocyte mitosis induced by conA and PHA.

---