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期 刊 ：中国中药杂志 1989年 14卷 07期 页码：47.

关键词：女贞子；抗炎作用；

Keywords:Fructus Ligustri Lucidi, aspirin, indomethacin, hydrocortisone, prostaglandin,

摘 要 ：女贞子对二甲苯引起小鼠耳廓肿胀、乙酸引起的小鼠腹腔毛细血管通透性增加及对角叉菜胶、蛋清、甲醛性大鼠足垫肿胀均有明显抑制作用,并显著降低大鼠炎症组织PGE的释放量。女贞子抑制大鼠棉球肉芽组织增生,同时伴有肾上腺重量的增加,对大鼠胸腺重量无明显影响。

Abstract:Fructus Ligustri Lucidi (FLL) inhibits the edema of hind Paw induced by injection of 1% carrageenin 0.1 ml, fresh egg 0.1 ml or 2.5% formaldehyde 0.1 ml in rats, and suppresses the increased vascular permeability induced hy 0.7% acetic acid in mice and the proliferation of granuloma induced by cottonpellet in rats. The swelling of ear induced by xylene in mice and the content of prostaglandin E in inflammatory tissue of rats are also decreased by FLL. FLL increases the weight of adrenal in rats, but has no marked effect on the weight of thymus of rata.

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