Matrix formulation of chaizhi cataplasma optimized by D-optimal mixture design combined with multiple mechanical indicators and its in vitro evaluation Matrix formulation optimizing of Periplaneta americana Cream by D-optimal mixture design Matrix formulation of Hanbishu Cataplasma optimized by D-optimal mixture design and research on its in vitro evaluation Solubilization of self-emulsifying drug delivery system (SEDDS) for curcumin components