A new compound from roots and rhizomes of Helleborus thibetanus Inhibitory effect of Helleborus thibetanus extracts on the proliferation of tumor cells and expression of COX-2 mRNA THE KARYOTYPE ANALYSIS OF HELLEBORUS THIBETANUS FRANCH Vegetative Organ Structures and Their Phylogenic Significance of Helleborus thibetanus Franch. (Ranunculaceae)