Abstract:Guard cell can sense and integrate multiple signals to regulate cell turgor and stomata movements. It is therefore regarded as a model system for studying the cross talk of phytohormones signaling. In this paper, ABA signal transduction and the cross talk of ABA signaling with other phytohormone signalings in guard cells are reviewed, to provide the emerging picture of phytohormone signaling network in guard cells. Future studies and potential application in crop production are also prospected.