Abstract:The effect of different N and P levels on yield under water stress were studied. The result showed that the height, number of tillering, index of leaves and spike rate of wheat, biomass and economic yield of winter wheat were increased with increasing moisture content. The yield and factors of yield components of wheat in N1P1treatment was the highest under the content of water 10.8% and 12.5% and the yield of winter wheat with N1P2 treatment was the highest under the 14.4% water content. Among different NP treatments, the yield of winter wheat with N2P2 treatment did not attained the highest under tested arid condition. The results also showed that the N1P1 and N1P2 treatments had good effect on drought-resistance for winter wheat under arid condition.