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作 者 ：谭宁华 王双明 杨亚滨 何敏

期 刊 ：云南植物研究 2003年 25卷 03期 页码：1-3

关键词：三七；人参；五加科；环二肽；内酰胺；

Keywords:Panax notoginseng,

摘 要 ：From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo(LeuThr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) including pyroglutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary bioactivity test showed that pyroglutamic acid and its nbutyl derivative have weak Ca2+ antagonistic activity.

Abstract:From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo(LeuThr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) including pyroglutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary bioactivity test showed that pyroglutamic acid and its nbutyl derivative have weak Ca2+ antagonistic activity.

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