Abstract:Chemical investigation of Dragon‘s blood resin from Dracaena cochinchinensis in Yunnan yielded five aromatic compounds, ethyl-p-hydroxy benzoate(l), 7,4‘-dihydroxyflavan (2), 7-hydroxy-4‘-methoxyflavan(3), 7,4‘-dihydroxyflavone (4) and lourerin (5) as well as a known steroid saponin (6). Three aromatic compounds showed antifungal activity. In addition, three kinds of domestic Dragon‘s blood resin from different regions and one kind of the imported were examined with TLC. The results indicated that the chemical constituents of the domestic dragon‘s blood resin were very similar, while the imported one was quite different.