作 者 :李勇军,李翠兵,何迅,廖尚高,兰燕宇,王爱民,王永林
期 刊 :中国中药杂志 2011年 36卷 4期 页码:458.
关键词:蓼科 ;荭草 ;化学成分 ;
Keywords:Polygonaceae , Polygonum oriental , chemical constituents ,
摘 要 :目的: 研究荭草Polygonum orientale 有效部位的化学成分。 方法 :应用色谱技术分离纯化,根据化合物的理化性质和波谱数据鉴定其结构。 结果 :分离并鉴定了7个化合物,分别为商陆素-3-O-β-D -半乳糖苷(ombuine-3-O-β-D -galactopyranoside, 1 ),商陆素-3-O- 芸香糖苷(ombuine-3-O- rutinoside, 2 ),色氨酸(tryptophan, 3 ),槲皮素-3-甲醚(quercetin -3-O- methyl ether, 4 ),山柰酚-3-O- (2″-O-α-L -鼠李糖基)-β-D -葡萄糖醛酸苷 5 ],槲皮素-3-O- (2″- O-α-L -鼠李糖基)-β-D -葡萄糖醛酸苷 6 ],槲皮素-3-O-β-D -葡萄糖醛酸苷(quercetin-3-O-β-D -glucuronide, 7 )。 结论 :化合物 4~7 为首次从该种植物中分离得到,化合物 1~3 为首次从该属植物中分离得到,并首次归属化合物 1 的1 H和13 C-NMR谱信号。
Abstract:Objective : To study the chemical constituents of the essential substance from the Polygonum oriental . Method : Chromatographic techniques were employed for isolation and purification of the constituents and their structures were determined by spectral analysis and chemical evidence. Result : Seven compounds were obtained and identified as ombuine-3-O-β-D -galactopyranoside ( 1 ),ombuine- 3-O- rutinoside ( 2 ), tryptophan ( 3 ), quercetin-3-O- methyl ether ( 4 ), kaempferol-3-O- (2″-O-α-L -rhamnopyranosyl)-β-D -glucuronopyranoside ( 5 ), quercetin-3-O- (2″-O-α-L -rhamnopyranosyl)-β-D -glucuronopyranoside ( 6 ), quercetin-3-O-β-D -glucuronide ( 7 ). Conclusion : Compounds 4-7 were isolated from P. oriental for the first time and compounds 1-3 were firstly obtained from the genus Polygonum . The total 1 H and 13 C-NMR date of compound 1 were assigned for first time.
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