Abstract:Objective: To study drug release of susained-released tablets of total puerariae flavones and investigate the evaluating method of sustained released preparations Chinese material medica susained-released preparation. Method: Rotating basket method and HPLC were employed to assess the characteristics of multi-component. Result: Under the selected chromatographic conditions, good HPLC fingerprint of the release of susained-released tablets of total puerariae flavones were obtained. Through the determination of 8 time-point samples,the release of susained-released tablet of total puerariae flavones had a well-balanced release behavior. Conclusion: The HPLC-UV fingerprint method was simple and reproducide, quality of tablets of total puerariae flavones can be controlled effectively by the method. The method could be applied to evaluate the the release of susained-released tablets of total puerariae flavones.