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期 刊 ：中国中药杂志 2008年 33卷 24期 页码：2950.

关键词：组分配伍；不稳定性心绞痛；血瘀证；炎性水平；

Keywords:component compatibility, unstable angina, blood stasis, level of inflammatory,

摘 要 ：目的：探讨活血药有效组分配伍的不稳定性心绞痛血瘀证患者血清白细胞（WBC），C反应蛋白(CRP)、白介素-6(IL-6)和肿瘤坏死因子α(TNF-α)的影响。方法：120例不稳定性心绞痛患者随机分为常规治疗组、组分配伍组、饮片组和血塞通组4组，每组30例；观察患者治疗前后的临床疗效、血脂指标及上述指标的变化。结果：组分配伍组治疗后临床疗效明显改善情，且WBC，CRP，IL-6及TNF-α，TC，TG水平较治疗前降低，差异有显著性(P＜0.05)，且低于其他3组治疗后(P＜0.05)。而HDL-C治疗后较治疗前升高，差异有显著性(P＜0.05)。结论 ：活血药有效组分配伍可有效治疗不稳定性心绞痛血瘀证，并能明显抑制其的炎性水平。

Abstract:Objective： To discussion the effects of Huoxue components of effective drug in treating unstable angina in patients with blood stasis WBC (WBC)， C-reactive protein (CRP)， interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α ). Method：one hundred and twenty cases of unstable angina were randomly divided into the conventional therapy group， component compatibility group， Pieces group and Xuesaitong group 4 groups， each with 30 cases. Observation of patients before and after treatment of clinical efficacy， blood lipid indicators and the indicators changes.Result： Component compatibility group after treatment clinical marked improvement in conditions， and the WBC， CRP， IL-6 and TNF-α， TC， TG levels lower than before treatment， there were significant differences (P<0.05)， and lower than the other three groups After treatment (P<0.05). And HDL-C after treatment than before treatment increased， there were significant differences (P<0.05). Conclusion： Huoxue-effective component compatibility can be effective treatment of unstable angina blood stasis， and could inhibit the inflammatory level.

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